Biological Activities and Chemical Composition of Xanthoria Lichens From Turkey
dc.authorscopusid | 55624671000 | |
dc.authorscopusid | 8411629800 | |
dc.authorscopusid | 57366492200 | |
dc.authorscopusid | 7102214656 | |
dc.authorscopusid | 55208137400 | |
dc.contributor.author | Mukemre, M. | |
dc.contributor.author | Zengin, G. | |
dc.contributor.author | Turker, R.S. | |
dc.contributor.author | Aslan, A. | |
dc.contributor.author | Dalar, A. | |
dc.date.accessioned | 2025-05-10T16:53:53Z | |
dc.date.available | 2025-05-10T16:53:53Z | |
dc.date.issued | 2021 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | Mukemre M., Department of Plant and Animal Production, Yuksekova Vocational School, Hakkari University, Hakkari, 30100, Turkey; Zengin G., Department of Biology, Faculty of Science, Selcuk University, Konya, Turkey; Turker R.S., Department of Pharmacology, Faculty of Pharmacy, Van Yuzuncu Yil University, Van, Turkey, Department of Neuroscience, Graduate School of Health Sciences, Yeditepe University, Istanbul, Turkey; Aslan A., Department of Pharmacology, Faculty of Pharmacy, Van Yuzuncu Yil University, Van, Turkey, Department of Biology, Faculty of Arts and Science, Kyrgyz-Turkish Manas University, Bishkek, Kyrgyzstan; Dalar A., Department of Pharmaceutical Botany, Faculty of Pharmacy, Van Yuzuncu Yil University, Van, Turkey | en_US |
dc.description.abstract | This study presents the biopharmaceutical potential and bioactive composition of Xanthoria lichens (X. candelaria, X. elegans, X. parietina) that wildly grown and traditionally utilized as medicine in North Eastern Anatolia, Turkey, which has specific microclimatic and ecological zones. Chromatographic findings revealed significant levels of parietin compound (35 to 49 mg/g extract), low levels of various fatty acids and a volatile compound; α-terpinene in the extracts. The extracts exhibited pronounced antioxidant potential through reducing and scavenging mechanisms; FCR: 33-38 mg gallic acid equivalent, FRAP: 511-815 μ mol Fe2+, ORAC: 1032-1355 μ mol Trolox equivalent per gram extract, respectively and DPPH: IC50: 1.1-2.7, ABTS: IC50: 2-2.3, CUPRAC: IC50: 0.7-1.2, phosphomolybdenum: IC50: 2-2.9, metal chelation: IC50: 1.3-2.3 mg extract/ml, respectively. Concerning enzyme inhibitory activities, the extracts effectively suppressed the activity of acetylcholinesterase (IC50: 0.5-0.75 mg/ml), butyrylcholinesterase (IC50: 0.7-1.1 mg/ml), tyrosinase (IC50: 0.6-0.7 mg/ml), amylase (IC50: 1.7-2 mg/ml), glucosidase (IC50: 0.6-3 mg/ml) and lipase (IC50: 55-79 μg/ml) enzymes. These findings showed that Xanthoria lichens are dominated by parietin as the major key compound and high-tolerated lichen taxa towards to different ecological and climatic conditions. These lichens might be promising sources of novel antioxidant and enzyme inhibitory activities such as Xanthoria candelaria as antioxidant and antilipase, Xanthoria elegans as anticholinesterase, and Xanthoria parietina as antiamylase and antiglucosidase. © 2021 Acta Biomedica Scientifica. All rights reserved. | en_US |
dc.identifier.doi | 10.21448/ijsm.994427 | |
dc.identifier.endpage | 388 | en_US |
dc.identifier.issn | 2148-6905 | |
dc.identifier.issue | 4 | en_US |
dc.identifier.scopus | 2-s2.0-85120799628 | |
dc.identifier.scopusquality | Q4 | |
dc.identifier.startpage | 376 | en_US |
dc.identifier.trdizinid | 1148509 | |
dc.identifier.uri | https://doi.org/10.21448/ijsm.994427 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/2921 | |
dc.identifier.volume | 8 | en_US |
dc.identifier.wosquality | N/A | |
dc.language.iso | en | en_US |
dc.publisher | Pamukkale University | en_US |
dc.relation.ispartof | International Journal of Secondary Metabolite | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Antioxidant | en_US |
dc.subject | Bioactives | en_US |
dc.subject | Enzyme Inhibition | en_US |
dc.subject | Natural Agent | en_US |
dc.subject | Xanthoria | en_US |
dc.title | Biological Activities and Chemical Composition of Xanthoria Lichens From Turkey | en_US |
dc.type | Article | en_US |