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Biological Activities and Chemical Composition of Xanthoria Lichens From Turkey

dc.authorscopusid 55624671000
dc.authorscopusid 8411629800
dc.authorscopusid 57366492200
dc.authorscopusid 7102214656
dc.authorscopusid 55208137400
dc.contributor.author Mukemre, M.
dc.contributor.author Zengin, G.
dc.contributor.author Turker, R.S.
dc.contributor.author Aslan, A.
dc.contributor.author Dalar, A.
dc.date.accessioned 2025-05-10T16:53:53Z
dc.date.available 2025-05-10T16:53:53Z
dc.date.issued 2021
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Mukemre M., Department of Plant and Animal Production, Yuksekova Vocational School, Hakkari University, Hakkari, 30100, Turkey; Zengin G., Department of Biology, Faculty of Science, Selcuk University, Konya, Turkey; Turker R.S., Department of Pharmacology, Faculty of Pharmacy, Van Yuzuncu Yil University, Van, Turkey, Department of Neuroscience, Graduate School of Health Sciences, Yeditepe University, Istanbul, Turkey; Aslan A., Department of Pharmacology, Faculty of Pharmacy, Van Yuzuncu Yil University, Van, Turkey, Department of Biology, Faculty of Arts and Science, Kyrgyz-Turkish Manas University, Bishkek, Kyrgyzstan; Dalar A., Department of Pharmaceutical Botany, Faculty of Pharmacy, Van Yuzuncu Yil University, Van, Turkey en_US
dc.description.abstract This study presents the biopharmaceutical potential and bioactive composition of Xanthoria lichens (X. candelaria, X. elegans, X. parietina) that wildly grown and traditionally utilized as medicine in North Eastern Anatolia, Turkey, which has specific microclimatic and ecological zones. Chromatographic findings revealed significant levels of parietin compound (35 to 49 mg/g extract), low levels of various fatty acids and a volatile compound; α-terpinene in the extracts. The extracts exhibited pronounced antioxidant potential through reducing and scavenging mechanisms; FCR: 33-38 mg gallic acid equivalent, FRAP: 511-815 μ mol Fe2+, ORAC: 1032-1355 μ mol Trolox equivalent per gram extract, respectively and DPPH: IC50: 1.1-2.7, ABTS: IC50: 2-2.3, CUPRAC: IC50: 0.7-1.2, phosphomolybdenum: IC50: 2-2.9, metal chelation: IC50: 1.3-2.3 mg extract/ml, respectively. Concerning enzyme inhibitory activities, the extracts effectively suppressed the activity of acetylcholinesterase (IC50: 0.5-0.75 mg/ml), butyrylcholinesterase (IC50: 0.7-1.1 mg/ml), tyrosinase (IC50: 0.6-0.7 mg/ml), amylase (IC50: 1.7-2 mg/ml), glucosidase (IC50: 0.6-3 mg/ml) and lipase (IC50: 55-79 μg/ml) enzymes. These findings showed that Xanthoria lichens are dominated by parietin as the major key compound and high-tolerated lichen taxa towards to different ecological and climatic conditions. These lichens might be promising sources of novel antioxidant and enzyme inhibitory activities such as Xanthoria candelaria as antioxidant and antilipase, Xanthoria elegans as anticholinesterase, and Xanthoria parietina as antiamylase and antiglucosidase. © 2021 Acta Biomedica Scientifica. All rights reserved. en_US
dc.identifier.doi 10.21448/ijsm.994427
dc.identifier.endpage 388 en_US
dc.identifier.issn 2148-6905
dc.identifier.issue 4 en_US
dc.identifier.scopus 2-s2.0-85120799628
dc.identifier.scopusquality Q4
dc.identifier.startpage 376 en_US
dc.identifier.trdizinid 1148509
dc.identifier.uri https://doi.org/10.21448/ijsm.994427
dc.identifier.uri https://hdl.handle.net/20.500.14720/2921
dc.identifier.volume 8 en_US
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Pamukkale University en_US
dc.relation.ispartof International Journal of Secondary Metabolite en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Antioxidant en_US
dc.subject Bioactives en_US
dc.subject Enzyme Inhibition en_US
dc.subject Natural Agent en_US
dc.subject Xanthoria en_US
dc.title Biological Activities and Chemical Composition of Xanthoria Lichens From Turkey en_US
dc.type Article en_US

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