Investigation of Dna-Binding Activities of Zinc(Ii) and Cobalt(Ii) Phthalocyanine Compounds With 3,4,5-Trimethoxybenzyloxy Substituents
| dc.authorscopusid | 56031715300 | |
| dc.authorscopusid | 55663235100 | |
| dc.contributor.author | Arslantas, Ali | |
| dc.contributor.author | Agirtas, Mehmet Salih | |
| dc.date.accessioned | 2025-05-10T17:03:54Z | |
| dc.date.available | 2025-05-10T17:03:54Z | |
| dc.date.issued | 2017 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Arslantas, Ali] Karabuk Univ, Sch Engn, Dept Biomed Engn, TR-78050 Karabuk, Turkey; [Agirtas, Mehmet Salih] Van Yuzuncu Yil Univ, Fac Sci, Dept Chem, TR-65080 Van, Turkey | en_US |
| dc.description.abstract | In this study, DNA-binding activities of previously synthesized tetrakis(3,4,5-trimethoxybenzyloxy)-substituted Zn(II) and Co(II) phthalocyanines (Pc4 and Pc5) have been chosen for the study. The interaction of synthesized tetrakis(3,4,5-trimethoxybenzyloxy)-substituted Zn(II) and Co(II) phthalocyanine compounds with CT-DNA was investigated by using UV/Vis titrimetric method, fluorescence spectroscopy, cyclic voltammetry, thermal denaturation profile, gel electrophoresis and viscosty measurement in a Tris-HCI buffer at pH 7.0. The results indicated that tetrakis(3,4,5-trimethoxybenzyloxy)-substituted Zn(II) and Co(II) phthalocyanines (Pc4 and Pc5) can interact with CT-DNA via intercalation binding mode. | en_US |
| dc.description.sponsorship | Committee for Scientific Research Projects at Karabuk University | en_US |
| dc.description.sponsorship | This study was supported by the Committee for Scientific Research Projects at Karabuk University. | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.doi | 10.1002/slct.201702362 | |
| dc.identifier.endpage | 11665 | en_US |
| dc.identifier.issn | 2365-6549 | |
| dc.identifier.issue | 35 | en_US |
| dc.identifier.scopus | 2-s2.0-85041840052 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 11659 | en_US |
| dc.identifier.uri | https://doi.org/10.1002/slct.201702362 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/5850 | |
| dc.identifier.volume | 2 | en_US |
| dc.identifier.wos | WOS:000418400400044 | |
| dc.identifier.wosquality | Q3 | |
| dc.language.iso | en | en_US |
| dc.publisher | Wiley-v C H verlag Gmbh | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Calf Thymus-Dann | en_US |
| dc.subject | Dna Binding | en_US |
| dc.subject | Phthalocyanine Compounds | en_US |
| dc.subject | Uv-Vis Spectroscopy | en_US |
| dc.title | Investigation of Dna-Binding Activities of Zinc(Ii) and Cobalt(Ii) Phthalocyanine Compounds With 3,4,5-Trimethoxybenzyloxy Substituents | en_US |
| dc.type | Article | en_US |