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Affinity To Some Inhibitors of Human Carbonic Anhydrase-1 and Bovine Carbonic Anhydrase

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Date

1996

Journal Title

Journal ISSN

Volume Title

Publisher

Marcel dekker inc

Abstract

The carbonic anhydrase Isoenzymes employed here have been purifield in high yields by affinity chromatograpy using different affinity gels(Sepharose4B-L-tyrosine-Benzensulfonamide). Inhibition effect of 2-Substituted-1,3,4-Thiadiazole-5-Sulfonamides on human carbonic anhydrase-I (HCA-I) and bovine carbonic anhydrase (BCA) have been determined. It was found that inhibition effects of these compounds on BCA and CA-I were very great.

Description

Keywords

Glaucoma, Carbonic Anhydrase, Inhibition

Turkish CoHE Thesis Center URL

WoS Q

N/A

Scopus Q

N/A

Source

Volume

31

Issue

8

Start Page

2017

End Page

2022