Van Yüzüncü Yıl Üniversitesi

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12 Kasım 1999 Düzce Depremi Artçı Depremlerinden Hesaplanan B ve P Değerlerinin Uzaysal ve Zamansal Dağılımı ve Gelecekteki Sismik Tehlike Açısından Değerlendirmeler
(2005) Alptekin, Ömer; Utkucu, Murat; Çetin, Canan
Gerek laboratuvar, gerekse gerçek deprem verilerini esas alan çalışmalardan deprem istatistiğinin frekans-büyüklük bağıntısındaki b değerinin yerkabuğundaki gerilim ile ters orantılı olduğu anlaşılmıştır. Bu çalışmada; 12 Kasım 1999 Düzce depreminin artçı deprem verilerinden bu depremin kırılma düzlemi ve bitişiğindeki Karadere ve Elmalık fay segmentleri boyunca yüzeyde ve derinlik boyutunda b değerleri ve artçı deprem azalım sabiti p'nin uzaysal dağılımı bir bilgisayar paket programı kullanılarak hesaplanmıştır. Düzce depremi için, Düzce fay segmenti üzerindeki pürüz boyunca haritalanan b=1.2-1.5 ve p=1-1.3 değerleri daha yüksek iken, Karadere (b=0.8-1.0, p=0.7-0.8) ve Elmalık (b=1.1-1.2, p=1.1) fay segmentleri boyunca daha düşük b değerleri elde edilmiştir. Ayrıca, b değerlerinin özellikle Düzce fayı üzerinde 1999 Düzce depremi öncesine göre yükseldiği görülmüştür. Bu durum, Karadere ve Elmalık fay segmentleri boyunca Düzce depremi sonrasında gerilme artışları (Düzce fayı üzerinde ise gerilme azalımı) olduğunu düşündürmektedir. Karadere fay segmentinin 17 Ağustos 1999 Kocaeli depremi sırasında kırılmış olması ve Elmalık fay segmenti üzerinde geçen yüzyıl içinde kaydadeğer bir deprem olduğuna ilişkin veri olmaması, 1999 Düzce depremi sonrasında bu fay üzerinde deprem tehlikesinin arttığı şeklinde yorumlanmıştır.
1800 Mhz Radio-Frequency Electromagnetic Radiation Induces Oxidative Stress in Rat Liver, Kidney and Brain Tissues
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Berköz, M.; Arslan, B.; Yıldırım, M.; Aras, N.; Yalın, S.; Çömelekoğlu, Ü.
Radio-frequency electromagnetic radiation (RF-EMR) represents one of the environmental factor that influence animal organism to stress. In this study we determined the oxidative stress parameters from rat liver, kidney and brain tissues that were exposed to chronic 1800 MHz RF-EMR. Our study was designed in 3 groups as 9 animals in each group. These are; control, sham and RF-EMR exposed group. The control group was not exposed to any procedure; sham group was housed in the same room under the same conditions with equal time period, except that the generator was turned off. RF-EMR exposed group was subjected to 1800 MHz RF-EMR emitted from the signal generator for 2 h per day for eight weeks. All animals that completed the experimental period were sacrificed and liver, kidney and brain tissues of all rats were isolated for analyzing malondialdehyde (MDA), nitric oxide (NO) and reduced glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activities. Liver, kidney and brain MDA and NO levels were higher and GSH level and SOD and catalase activities were significantly lower in RF-exposed group than control and sham groups (p<0.001). No significant difference was observed in terms of tissue MDA, GSH and NO levels and SOD and catalase activities between control and sham groups in each tissue. The results of our study shows that RF-EMR may act as an environmental stressor and cause oxidative and nitrosative damage in liver, kidney and brain tissues. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
18f Fdg Pet/Ct in a Child With Gliomatosis Cerebri
(Elsevier Doyma Sl, 2013) Surucu, E.; Mutafoglu, K.; Ince, D.; Cakmakci, H.; Demiral, A.; Polack, B. Degirmenci
4d Oranı ve Parmak Boyları Açısından Obsesif Kompulsif Bozukluk, Yaygın Gelişimsel Bozukluk Tanısı Konulan Çocuklar ve Sağlıklı Kontrollerin Karşılaştırılması
(2016) Bahcelıoglu, Meltem; Buru, Ece; Taner, Hande Ayraler; Gözil, Rabet; İşeri, Elvan
Amaç: Obsesif kompulsif bozukluk ( OKB) ve otizm, tekrarlayıcı davranışlar gibi bazı ortak özelliklere sahiptirler. Prenatal androjenlere maruziyet ile ilişkili olduğu düşünülen, cinsiyetler arasında faklılık gösteren; 2. Parmağın 4. Parmağa oranının (2d:4d) otizmde daha çok \"erkek benzeri\" olduğu bildirilmektedir. Bu çalışmanın amacı ortak özellikleri bulunan OKB ve otizm grubunun 2d:4d oranı ve parmak uzunlukları açısından karşılaştırılmasıdır. Yöntem: Bu çalışmaya 6-18 yaşları arasında olan OKB tanısı konulan 15, Yaygın gelişimsel bozukluk ( YGB ) tanısı konulan 12 ve herhangi bir psikiyatrik bozukluğu olmayan 54 erkek sağlıklı çocuk-ergen dahil edilmiştir. Hasta grubunda OKB ve YGB tanısı ayrıntılı klinik değerlendirme sonucunda DSM IV-TR tanı kriterlerine göre konulmuştur. Değerlendirme sonrasında dijital kompas yardımıyla çocuk ve ergenlerin el uzunluğu, el genişliği, parmak uzunlukları ölçülmüştür. Bulgular : Kontrol, OKB ve YGB grupları arasında sağ ve sol 2d:4d oranı yönünden istatistiksel olarak anlamlı farklılık saptanmamıştır. Buna karşın, YGB grubunda sağ el 2. ve 3.parmaklar ile, sol el 2,3,4. parmakların kontrol grubuna göre daha kısa olduğu saptanmıştır. Sol el uzunluğu YGB grubunda OKB grubuna göre daha kısa olarak saptanırken, sağ 2. ve sol 3. parmak uzunluğu YGB grubunda kontrol ve OKB grubuna göre daha kısa olarak bulunmuştur. Sonuç : Bu çalışmada 2d:4d oranı açısından OKB, YGB ve sağlıklı kontroller arasında herhangi bir farklılık saptanmazken; YGB grubunda bazı parmak boylarının kontrol grubuna göre daha kısa olduğu tespit edilmiştir. Bu bulgu YGB grubunda taranabilecek bir dismorfolojik bir bulgu olabilir ancak daha geniş örneklemlerle yapılacak ileri çalışmalara ihtiyaç duyulmaktadır.
8-Ohdg Levels in Patients With Allergic Rhiniti
(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2011) Onbasi, Kevser; Noyan, Tevfik; Cebi, Aysegl; Kiroglu, Faruk
Objective: Respiratory allergies like allergic rhinitis and allergic asthma are more frequently observed worldwide. Chronic inflammation in the respiratory tract is observed in these diseases. Oxidative stress contributes to this inflammation in the respiratory airways. 8-OHdG is a marker of oxidative stress. The aim of our study was to investigate the 8-OHdG levels in patients with respiratory allergy. Material and Methods: 23 patients with allergy consisting of 11 men and 12 women and 23 healthy controls were enrolled to the study. Results: 8-OHdG levels were found to be higher in allergic patients in comparison to healthy controls but it was not statistically significant. Conclusion: The reason for not significantly high levels of 8-OHdG levels as a marker of oxidative stress in respiratory allergy may attribute to the factor that the inflammation in respiratory allergy is less intensive in comparison to the inflammation in atopic dermatitis.
Ab-Initio Study of Csgecl3 Compound in Paraelectric and Ferroelectric Phases
(Taylor & Francis Ltd, 2016) Erdinc, Bahattin; Secuk, Mehmet Nurullah; Aycibin, Murat; Gulebagan, Sinem Erden; Dogan, Emel Kilit; Akkus, Harun
Structural optimization, electronic energy band structure, density of states, optical, lattice dynamic and thermodynamic properties of CsGeCl3 compound in paraelectric and ferroelectric phases were investigated using the DFT in the GGA and LDA approximations. The obtained results of CsGeCl3 crystal were compared with the available theoretical and experimental results and have been found to be in good agreement with these results.
Abc, Ved, and Abc-Ved Matrix Analyses for Inventory Management in Community Pharmacies: a Case Study
(Society of Pharmaceutical Sciences of Ankara (FABAD), 2022) Dursa, E.; Arslan, M.
Inventory control methods should be used effectively in community pharmacies to determine and obtain the needs for pharmaceuticals and non-pharmaceutical products at appropriate times and with proper procedures. An effective stock control provides positive outputs in the community pharmacy’s economy, the quality of the service to be provided, and the pharmacy’s image. In this context, within the scope of this study, it aims to evaluate ABC, VED, and ABC-VED matrix analyses in terms of community pharmacies. In the study, ABC, VED, and ABC-VED matrix analyzes were applied using the inventory data of a community pharmacy serving in the city center of Van for the 2019-2020 financial year. For this purpose, firstly, annual consumption and expenditure data for each pharmacy item specified for the 2019-2020 financial year were collected. The data were then transferred to an MS Excel spreadsheet, and statistical analysis was performed using MS Excel statistical functions. As a result of ABC-VED analysis, it was determined that the drugs in the first category were of great importance for effective stock control, the drugs in the second category were of medium importance, and the drugs in the third category were of low importance. They are because the pharmacy from which the research data is taken is close to the family health center and the socioeconomic structure of the pharmacy’s environment. This categorization is thought to be appropriate. © 2022 Society of Pharmaceutical Sciences of Ankara (FABAD). All rights reserved.
Abo and Rh Blood Groups Frequency in Men and Women Living in Eastern Turkey
(2006) Dilek, I.; Demir, C.; Bay, A.; Akdeniz, H.; Öner, A.F.
Objective: ABO and Rh blood groups which are basic for determination of blood compatibility consist of the most important tests of blood center. In this study, we aimed to find out the rates of ABO and Rh blood groups in male and female donors in our region. Therefore, donors attending to our blood center within the last five years were investigated taken into account their gender. Methods: Blood groups were examined by gel-centrifugation or tube agglutination methods. Results: Out of totally 33.193 individuals, 14.716 were female (44.3%) and 18.477 males (55.7%), and average age was 34 (range 20-60 years old). Taken into account the whole donors, A blood type was found as 43.8%, O blood type 30.8%, B blood type 16.2% and AB blood type 8.6% in rate. With respect to blood type frequency in genders group A was in the rate of 44.1% and 43.6%, group O 31% and 30.5%, group B 16.3% and 16.1% and group AB 8.6% and 9.8% in women and men, respectively. The Rh positivity rate into totally whole donors was 85.5%, being 86.0% in men and 84.8% in women. Conclusion: ABO and Rh blood groups rates were very near to each other in women and men, and also the average rate was very similar to averages in Turkey.
Accommodation Spasm Following Tetanus Diphtheria (Td) Vaccination
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Batur, M.; Artuç, T.; Seven, E.; Tekin, S.
Accommodation spasm is a rare condition that presents with pseudomyopia usually in children and young adults. Most of the cases are associated with emotional conditions that causes functional spasm. Sometimes, an underlying organic cause can be detected. Tetanus-diphtheria vaccine (Td) is a combined vaccine in toxoid form and performs to prevent infectious diseases caused by Clostiridium tetani and Corynebacterium diphtheriae, respectively. In this case report, we present the clinic features of a 13-year-old girl who applied with decreased vision after Td vaccination and diagnosed with isolated accommodation spasm. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Accumulation of Heavy Metals on Bacillus Cereus and Pseudomonas Aeruginosa Strains Isolates From the Van Regional Soils in Turkey
(Asian Journal of Chemistry, 2007) Dostbil, Nursel
This investigation was conducted in order to determine the overall intracellular accumulation of Co2+, Cd2+ and Pb2+ on Bacillus cereus and Pseudonzonas aeruginosa which isolated from the soil samples collected from Van region. According to the results of the investigation, intracellular accumulation was observed to increase in wild type strains of B. cereus T 124 and P aeruginosa N 48 through the applications of Co2+, Cd2+ and Pb2+ (0.25, 0.5, 1, 2 and 4 mM). However, both the type of bacteria and the effect of various heavy metals caused different accumulation in two bacteria. In the three of the heavy metals put into application, B. cereus T 124 was found to have much more accumulation than P. aeruginosa N 48. The intracellular accumulation of Cd and Co metal was observed to be greater in B. cereus T 124 strain whereas the intracellular accumulation Pb2+ metal was seen to be much greater in P aeruginosa strain. The highest amount of accumulation was observed for Pb2+.
Accurately Localizing the Thyroid Tissue in Mature Cystic Teratoma of Ovary by Single-Photon Emission Computerized Tomography/Computerized Tomography
(Wolters Kluwer Medknow Publications, 2015) Demir, Yusuf; Ucler, Rifki; Alkis, Ismet; Bulut, Gulay
A 30-year-old woman with hyperthyroidism was admitted to hospital. Although increased thyroid function was found, the gland was normal in ultrasonography (USG). Additionally, thyroid iodine uptake and Tc-99m pertechnetate scintigraphy was normal. Abdomen USG detected a cystic pelvic mass in left ovary. A whole-body scan was performed 48 hours after oral ingestion of 29.6 MBq (0.8 mCi) 1-131 (iodine-131) revealed a round structure located to the left lower abdomen. Iodine uptake was detected in this cyst which was compatible with functional thyroid tissue demonstrated by SPECT/CT. The patient was underwent surgical operation and histopathology confirmed mature cystic teratoma. Accurate localization and depiction of thyroid tissue in ovary mass was provided with SPECT/CT.
Actions of Resveratrol and Serotonin Added To Stored Bloods on Lipid Peroxidation and Oxidative Dna Damage
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Huyut, Z.; Şekeroğlu, M.R.; Alp, H.H.; Balahoroğlu, R.; Çokluk, E.
Stored blood for use in diseases such as acute blood loss, injury and anemia can be maintained for about a month. It was reported that some negative changes called "storage lesions" occur in stored bloods time dependently. In order to delay these changes, preservatives are added to stored bloods. In this study, we aimed to determine the effects of resveratrol and serotonin on oxidative DNA and mitochondrial damage and lipid peroxidation in stored blood. Blood was taken from 10 volunteers to different blood bags and each blood was separated into 3 groups (control, resveratrol and serotonin groups). Malondialdehyde (MDA), ubiquinone-10 (CoQ10) and 8-hydroxy-2-deoxyguanosine/106deoxyguanosine (8-OHdG/106dG) levels were determined at baseline and on the 7th, 14th, 21st and 28th day after addition of resveratrol and serotonin. MDA, CoQ10 and 8-OHdG/106dG levels increased over time in the control and serotonin groups (p<0.05). However, resveratrol protected against the time-dependent increase in MDA and CoQ10 values (p>0.05). MDA and CoQ10 levels were significantly lower in the resveratrol-treated group on the 21st and 28th days compared with the other groups (p<0.05). These results show that oxidation sensitivity increased time dependently in stored blood. However, the addition of resveratrol allowed the extension of the blood’s shelf life by protecting against increased lipid peroxidation and oxidized CoQ10. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Active Tectonic Setting and Paleoseismicity of the Sancak-Uzunpazar Fault Zone
(Afet ve Acil Durum Yonetimi Baskanligi (AFAD), 2021) Selcuk, A.S.; Erturac, M.K.; Karabacak, V.; Sancar, T.; Kul, A.O.; Yavuz, M.A.
Sancak-Uzunpazar Fault Zone is N40E-trending sinistral shear zone that has a 50 km length and 5 km width between Karakocan (Elazığ) in southwest and Kaynarpınar (Bingöl) in northeast. The fault extends parallelly to East Anatolian Fault is bounded by the North Anatolian Fault to the northeast and Karakoçan Fault to the southeast. Herein, morphological features, the tectonic setting of the Sancak-Uzunpazar Fault Zone and the first paleoseismological studies on it is represented. The Sancak-Uzunpazar Fault Zone is consist of two parallel segments (called East and West) with a 1.5 km distance. Conducted field studies and aerial photogrometry show that the segments exhibit morphological features like faceted surfaces, faulted scarps, shutter ridges, and offset streams. Especially, average offsets are about 7-12 m along the eastern segment while the cumulative maximum offset reaches 1.1 km. Moreover, revealed paleoseismological data show evidence of at least two surface ruptures during Holocene. Obtained morphological data reveal that the Sancak-Uzunpazar Fault Zone may have a relatively lower slip rate when compared to other active faults in the region and the reflection of the slip rate to the morphology is more evident in the eastern segment. © 2022 Turk Deprem Arastirma Dergisi. All rights reserved.
The Activities of Gst Isozymes in Stomach Tissues of Female Obese Patients
(Walter de Gruyter Gmbh, 2020) Yilmaz, Can; Bulus, Hakan; Oguztuzun, Serpil; Cihan, Mehmethan; Fidan, Ceylan
Objectives: Obesity has become an important public health problem because of its increasing prevalence and relation with many diseases and mortality. Studies have shown its association with oxidative stress. In this study, the effect of obesity on total amount of thiol and some glutathione S-transferase (GST) isozymes were investigated which could serve as an important criteria in dose adjustment of some certain drugs in obese. Methods: The gastric tissues removed by gastrectomy operation from 29 morbid obese female patients were analysed for thiol levels and activities of total GST, GSTT1-1 and GSTM1-1. Patients were grouped according to age, presence of hypertension and/or diabetes, and family history. Results: The average total thiol was 131.22 (+/- 7.74) nmol/mg protein with no significant differences in between the groups. GSTT1 specific activities were about 20% higher in four groups: with ages over 35 years old, with hypertension, without diabetes and finally without family history, with respect to other groups. The differences between total GST and GSTM1 activity levels of experimental groups were not significant. Conclusions: This is the first study to compare activities of GST isozymes and total thiol content in the stomach tissues of obese female patients accompanying some common metabolic disorders, age and family history.
Activity, Acute and Sub-Acute Toxicity and Safety Assesment of the Hydroalcholic Root Extract of Diplotaenia Turcica
(Agricultural Research Communication Centre, 2018) Ozdek, U.; Basbugan, Y.; Yildirim, S.; Boga, M.; Firat, M.; Deger, Y.
Diplotaenia turcica is widely utilized in conventional treatment in the east of Turkey. Due to the insufficient data on the safety profile, the acute and sub acute toxicity of Diplotaenia turcica was determined. Furthermore, total phenolic content, flavonoid content and antioxidant activity of the extract were determined. The acute toxicity of hydroalcoholic root extract of Diplotaenia turcica (HREDT) was evaluated in mice after administration of single oral dose at the 5000 mg/kg (acute model) and rat after 28 days orally administration at the dose range of 250, 500 and 1000 mg/kg (subacute model). According to result, the LD50 value of HREDT was found to be greater than 5000 ing/kg. In sub acute toxicity study, no statistically significant differences were observed in the values of hematological and pathological parameters in comparison with control group. It was determined that the glucose, triglyceride, cholesterol and LDL levels exerted a significant effect depending on the HREDT doses. The results from the present study found out that HREDT did not produce any toxic effects or deaths in animals for both single and chronic administration. Additionally, HREDT showed moderate antioxidant activities and exhibited relatively notable total phenolic content.
Acute Necrotizing Fasciitis Developed Due To Staphylococcal Infection During Neonatal Varicella
(2006) Tuncera, O.; Ataşa, B.; Kirimia, E.; Akbayrama, S.; Atikb, B.; Çaksena, H.
Although varicella acquired during childhood normally has a benign course, complications may occur during the course of the disease. Cellulitis sometimes occurs as a result of bacterial superinfection. When caused by A-group Streptococci cellulitis may evolve into necrotizing fasciitis leading to necrosis of deep tissues. We have found treatment using parenteral antibiotics, intensive supplementary therapy and surgical debridement of necrotic tissues to be effective. A case of Staphylococcal necrotizing fasciitis in a neonate is reported. © 2006 - IOS Press and the authors.
Acute Renal Failure Due To Light Chain Cast Nephropathy
(2011) Bulut, G.; Kösem, M.
Myeloma cast nephropathy, also known Bence Jones cast nephropathy or myeloma kidney is the most common form of renal disease associated with multiple myeloma. Clinically, it may present as progressive renal insufficieny or acute renal failure. We describe a case of multiple myeloma who presented with acute renal failure due to light chain cast nephropathy and had a primary diagnosis made by renal biopsy. A renal biopsy was performed for acute renal failure in a 44 year old female patient. The renal biopsy showed numerous dilated tubules filled with pink eosinophilic fractured casts surrounded at places by multinucleated giant cells and accompanied by moderate interstitial infiltrate consisting of lymphomononuclear cells. There was tubular atrophy with interstitial fibrosis. The renal biopsy is occasionally the first test indicative of myeloma in a patient with acute renal failure of seemingly unknown origin. Thus the microscopic appearance of the tubules in this biopsy is easy to appreciate and is diagnostic of light chain cast nephropathy.
Acute Stroke Management in Türkiye: Intravenous Tissue Plasminogen Activator and Thrombectomy Nörotek: Türkiye Neurology Single Day Study
(Galenos Publ House, 2023) Topcuoglu, Mehmet Akif; Ozdemir, Atilla Ozcan; Arsava, Ethem Murat; Gunes, Aygul; Aykac, Özlem; Gencer, Elif Sarionder; Ozturk, Serefnur
Objective: To reveal the profile and practice in patients with acute stroke who received intravenous tissue plasminogen activator (IV tPA) and/or neurointerventional therapy in Turkiye. Materials and Methods: On World Stroke Awareness Day, May 10, 2018, 1,790 patients hospitalized in 87 neurology units spread over 30 health regions were evaluated retrospectively and prospectively. Results: Intravenous tPA was administered to 12% of 859 cases of acute ischemic stroke in 45 units participating in the study. In the same period, 8.3% of the cases received neurointerventional treatment. The rate of good prognosis [modified Rankin score (mRS) 0-2] at discharge was 46% in 83 patients who received only IV tPA [age: 67 +/- 12 years; National Institutes of Health Stroke Scale (NIHSS): 12 +/- 6; hospital stay, 24 +/- 29 days]; 35% in 51 patients who underwent thrombectomy (MT) alone (age: 64 +/- 13 years; NIHSS: 14.1 +/- 6.5; length of hospital stay, 33 +/- 31 days), 19% in those who received combined treatment (age: 66 +/- 14 years; NIHSS: 15.6 +/- 5.4; length of hospital stay, 26 +/- 35 days), and 56% of 695 patients who did not receive treatment for revascularization (age: 70 +/- 13 years; NIHSS: 7.6 +/- 7.2; length of hospital stay, 21 +/- 28 days). The symptom-to-door time was 87 +/- 53 minutes in the IV treatment group and 200 +/- 26 minutes in the neurointerventional group. The average door-to-needle time was 66 +/- 49 minutes in the IV tPA group. In the neurothrombectomy group, the door-to-groin time was 103 +/- 90 minutes, and the TICI 2b-3 rate was 70.3%. In 103 patients who received IV tPA, the discharge mRS 0-2 was 41%, while the rate of mRS 0-1 was 28%. In 71 patients who underwent neurothrombectomy, the mRS 0-2 was 31% and mRS 0-1 was 18%. The door-to-groin time was approximately 30 minutes longer if IV tPA was received (125 +/- 107 and 95 +/- 83 minutes, respectively). Symptomatic bleeding rates were 4.8% in IV recipients, 17.6% among those who received only MT, and 15% in combined therapy. Globally, the hemorrhage rate was 6.8% in patients receiving IV tPA and 16.9% in MT. Conclusion: IV thrombolytic and neurointerventional treatment applications in acute ischemic stroke in Turkiye can provide the anticipated results. Heterogeneity has begun to be reduced in our country with the dissemination of the system indicated by the "Directive on Health Services to be Provided to Patients with Acute Stroke."
An Addition To the Flora of Turkey: Salvia Reuteriana (Lamiaceae), With Contributions To Its Taxonomy
(Research Institute of Forests and Rangelands of Iran, 2020) Firat, M.
Salvia reuteriana Boiss. (Lamiaceae), a new record for the flora of Turkey, is described. It is collected in Şırnak province, southeastern Anatolia. Salvia reuteriana was previously known from Iraq and Iran, with the type specimen of the species from Iran. Morphological description, photographs and distribution map of the new record are presented. © 2020, Research Institute of Forests and Rangelands of Iran. All rights reserved.
Adenoid Hypertrophy in Adults: Clinical and Morphological Characteristics
(Sage Publications Ltd, 2008) Yildirim, N.; Sahan, M.; Karslioglu, Y.
This study compared the aetiology and pathological characteristics of adult and childhood adenoid hypertrophy (AH). Clinical and morphological features and accompanying otolaryngological pathologies were recorded in 40 adults and 23 children undergoing adenoidectomy for obstructive AH. Both AH forms were similar in terms of symptomatology and associated inflammations. There were, however, significant differences in otitis media rate, with effusion and dullness, and retraction in the eardrum both more prevalent in childhood AH. Adult AH was associated with nasal septum deviation in 25.0% of patients. Histopathological features of adenoidal lymphoid tissue were dissimilar in the two groups: numerous lymph follicles with prominent germinal centres was the chief finding in childhood adenoids, whereas adult adenoids showed chronic inflammatory cell infiltration and secondary changes (e.g. squamous metaplasia). These results underline the importance of considering AH as a cause or contributing factor in nasal obstruction and related pathologies in adults and supports the theory that it represents a long-standing inflammatory process rather than being a novel clinical entity.

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