Evaluation of Antibiotic Resistance in Acinetobacter Baumannii Strains Isolated From Various Clinical Samples

Abstract

Objective: Treatment of Acinetobacter baumanii infections has become increasingly difficult, due to the high resistance rates against commonly administered antibiotics. This study aims to determine the antibiotic resistance of A. baumannii strains isolated in our hospital. Methods: Antibiotic resistances of 377 A. baumannii strains isolated from various clinical specimens between 2007-2011 were assessed retrospectively. The isolates were identified by conventional methods and Phoenix 100 (Becton Dickinson Co., Sparks, MD, USA) automated system. Antibiotic susceptibility tests were performed according to the standards of Clinical and Laboratory Standards Institute. Results: Colistin resistance was not observed, and resistances to the other antibiotics were found to be 64% to amikacin, 55% to tetracycline, 71% to imipenem, 72% to meropenem, 89% to cefoperazone-sulbactam and 92% to ciprofloxacin, 90% to gentamicin, 94% to ceftazidime, 96% to piperacillin-tazobactam, 95% to cefepime and 96% to cefotaxime. Conclusions: Knowledge of susceptibilitys rates of these bacteria is essential, especially in situations compelling empirical treatment.