The Efficacy of Cloxacillin and Micanfin in Multifactorial Conjunctivitis Treatment in Van Cats

Abstract

This study was performed on 121 Van Cats at the Van Cat Research Center of the Yucuncu YiI University. Out, of 121 cats 20 showed an uni- or bilateral conjunctivitis. The animals were of both sex aging between 1-9 years. The following symptoms were observed in 20 cats with conjunctivitis: serous or seromucous lacrimation, hyperemia and oedema in the conjunctiva and desquamation around their eyes. Hair samples together with hair follicules were taken from comissura medialis and used for bacteriologial and fungal culture. After cultivation, Staphylococcus spp. in 19 cats, Streptococcus spp. in 7 cats and Microsporum spp. in 2 cats were isolated. All the bacteria detected were sensitivite to cloxacillin and to some other antibiotics according to the antibiogram. Cloxacillin (Optidox opht. pom., Sanovel) was applied to both eyes of the all 20 cats. After drug application, 18 cats out of 20 (90%) showed recovery signs starting from 24 hours to 72 hours. However, clinical signs in two cats (10 %) had not disappeared at all. 1.72 hours after drug application, hair samples were taken again for bacteriological analysis. With the exception of these two samples collected from the cats with no clinical improvement, the other 18 samples did not show any bacterial growth. The 2 cats recovered after a second cloxacillin application. The conjunctivitis symptoms disappeared and bacteriological tests made 144 hours after the treatment were negative. After bacteriological elimination, the vaccine Micanfin (Micanfin flk. BioVeta) against Microsporum canis was injected intra-muscularly twice at 14 days intervals. Allergic reactions were not observed on the cats after vaccination. Fungal agents couldn't also be detected 25 and 40 days after vaccination. As a result; cloxacillin was an effective antibiotic in the conjunctivitis caused by Staphylococcus spp., and Streptococcus spp. and Micanfin can safely be used in Van cats without any side effect.