In Vitro Enzyme Inhibitory Activity of Ten Ferulago W. Koch Species Growing in Turkey

dc.contributor.author Akkol, Esra Kupeli
dc.contributor.author Gunbatan, Tugba
dc.contributor.author Gurbuz, Ilhan
dc.contributor.author Duman, Hayri
dc.contributor.author Kilic, Ceyda Sibel
dc.contributor.author Ilhan, Mert
dc.date.accessioned 2025-05-10T17:13:56Z
dc.date.available 2025-05-10T17:13:56Z
dc.date.issued 2022
dc.description Kupeli Akkol, Esra/0000-0002-5829-7869; Kilic, Ceyda Sibel/0000-0003-2905-7628; Gurbuz, Ilhan/0000-0002-3670-0899; Gunbatan, Tugba/0000-0002-1138-3145 en_US
dc.description.abstract Ferulago species are traditionally used for the treatment of skin diseases, bronchitis, and depression, to increase body strength, as an immunostimulant, aphrodisiac and sedative in Anatolia. In this study, hyaluronidase, collagenase and elastase inhibitory potential relevant to wound healing activities of ethanol extracts from the roots of ten Ferulago species [F. cassia Boiss., F. humilis Boiss., F. isaurica Pesmen, F. longistylis Boiss., F. mascrosciadia Boiss. & Balansa, F. sandrasica Pesmen & Quezel, F. setifolia K. Koch., F. silaifolia (Boiss.) Boiss., F. trojana Akalin & Pimenov formerly known as F. sylvatica (Besser) Rchb. and F. syriaca Boiss.] were investigated. Ethanol extracts of F. mascrosciadia and F. syriaca were the most active ones against collagenase and elastase, respectively. In vitro wound healing activity of ten Ferulago species is reported for the first time in the current study. en_US
dc.description.sponsorship TUBITAK [115S364] en_US
dc.description.sponsorship This research was partially funded by TUBITAK (115S364). en_US
dc.identifier.doi 10.1590/1678-4324-2022210207
dc.identifier.issn 1516-8913
dc.identifier.issn 1678-4324
dc.identifier.scopus 2-s2.0-85131420385
dc.identifier.uri https://doi.org/10.1590/1678-4324-2022210207
dc.identifier.uri https://hdl.handle.net/20.500.14720/8344
dc.language.iso en en_US
dc.publisher inst Tecnologia Parana en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Ferulago en_US
dc.subject Collagenase en_US
dc.subject Elastase en_US
dc.subject Hyaluronidase en_US
dc.subject Wound en_US
dc.title In Vitro Enzyme Inhibitory Activity of Ten Ferulago W. Koch Species Growing in Turkey en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.id Kupeli Akkol, Esra/0000-0002-5829-7869
gdc.author.id Kilic, Ceyda Sibel/0000-0003-2905-7628
gdc.author.id Gurbuz, Ilhan/0000-0002-3670-0899
gdc.author.id Gunbatan, Tugba/0000-0002-1138-3145
gdc.author.scopusid 23096992900
gdc.author.scopusid 57188819718
gdc.author.scopusid 6602792411
gdc.author.scopusid 7006403338
gdc.author.scopusid 6507159905
gdc.author.scopusid 56020070400
gdc.author.wosid Akkol, Esra/Abi-4678-2020
gdc.author.wosid Günbatan, Tuğba/Aha-9058-2022
gdc.author.wosid Gurbuz, Ilhan/Ahb-3295-2022
gdc.author.wosid Ilhan, Mert/Hlh-6199-2023
gdc.author.wosid Kilic, Ceyda Sibel/F-8057-2014
gdc.coar.access open access
gdc.coar.type text::journal::journal article
gdc.description.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
gdc.description.departmenttemp [Akkol, Esra Kupeli; Gunbatan, Tugba; Gurbuz, Ilhan] Gazi Univ, Fac Pharm, Dept Pharmacognosy, Ankara, Turkey; [Duman, Hayri] Gazi Univ, Fac Sci, Dept Biol, Ankara, Turkey; [Kilic, Ceyda Sibel] Ankara Univ, Fac Pharm, Dept Pharmaceut Bot, Ankara, Turkey; [Ilhan, Mert] Van Yuzuncu Yil Univ, Fac Pharm, Dept Pharmacognosy, Van, Turkey en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q2
gdc.description.volume 65 en_US
gdc.description.woscitationindex Science Citation Index Expanded
gdc.description.wosquality Q4
gdc.identifier.wos WOS:000820488800001
gdc.index.type WoS
gdc.index.type Scopus

Files