Pharmacokinetics of Long Acting and Conventional Formulations of Oxytetracycline in Goats

Abstract

Oxytetracycline (OTC) is a broadspectrum antibiotic extensively used for the treatment of a variety disease and is active not only against a variety of gram (+) and gram (-) organisms, but also against mycoplasma, ehrlichia, rickettsiae, clarnydia and anaplasma. The pharmacokinetics of OTC may be changed by parameters such as species, age, health, route of administration and other conditions. There is a paucity of information on the pharmacokinetics of OTC in goats. Therefore the present study was performed to investigate the pharmacokinetics of OTC after intravenous and intramuscular administrations of both conventional (CF) and long-acting (LA) formulations in Colored Mohair goats of Turkey.