The Effects of Plant Growth Regulators on Activity of Eight Serum Enzymes in Vitro

Abstract

In this study, the effects of plant growth regulators (PGRs). Indole Acetic Acid (IAA), 2,3,5-Triiodo Benzoik Acid (TIBA) and Kinetin on human serum enzymes, myocardial creatine kinase (CK-MB), amylase, creatine kinase (CK), aspartate amino transferase (AST), serum glutamyl pruvic transferase (SGPT). alkaline phosphatase (ALK-P), δ glutamyl transferase (GGT-P) and lactate dehydrogenase (LDH) were investigated (in vitro). I50 values of chemicals caused inhibition were determined by means of activity percentage - [I] diagrams. The results showed that IAA was an activator rather than an inhibitor. It only inhibited AST activity, but increased activities of CK, CK-MB, amylase, ALK-P and LDH. However, IAA ineffected on SGPT and GGT-P. Both TIBA and Kinetin inhibited CK-MB, but either chemicals ineffected on CK, amylase, ALK-P, GGT-P. On the other hand, TIBA ineffected on SGPT and LDH, while Kinetin increased activity of the same enzymes. In conclusion, it was showed that the studied chemicals weakly inhibited enzymes.