Successful Conservative Management of Primary Hyperparathyroidism Diagnosed During Pregnancy

Abstract

Introduction: Primary hyperparathyroidism (PHP) a rare condition that leads to severe maternal and fetal complications in pregnancy. In this report, we aimed to present the successful conservative medical treatment of PHP diagnosed during pregnancy. Case Presentation: A 32-year-old pregnant woman was referred to our clinic at 14 weeks of gestation with severe vomiting, chronic constipation and proximal muscle weakness. According to the clinical presentation, PHP was diagnosed on the basis of biochemical and ultrasonographic findings. The patient was treated with high fluid intake, low calcium diet, oral phosphate supplementation and intramuscular injection of calcitonin. At 38 weeks of gestation, healthy infant was delivered by cesarean section with mild preeclampsia. Conclusion: Treatment options of PHP, including medical and surgical therapy are debated in the literature. Early diagnosis and effective management may reduce perinatal mortality and morbidity. Although surgical treatment in the second trimester is the definitive therapy, conservative management can be preferred in mild cases of PHP in pregnancy.