Serum Procarboxypeptidase a and Carboxypeptidase a Levels in Pancreatic Disease
| dc.authorid | Sumer, Aziz/0000-0003-3938-3363 | |
| dc.authorid | Kemik, Ozgur/0000-0002-4612-1428 | |
| dc.authorscopusid | 6504566099 | |
| dc.authorscopusid | 35332340400 | |
| dc.authorscopusid | 26653741600 | |
| dc.authorscopusid | 10242147700 | |
| dc.authorscopusid | 36476941100 | |
| dc.authorscopusid | 6504310163 | |
| dc.authorscopusid | 6504310163 | |
| dc.authorwosid | Begenik, Huseyin/Lkl-8263-2024 | |
| dc.authorwosid | Kemik, Ozgur/Mgb-2153-2025 | |
| dc.authorwosid | Sümer, Aziz/Ahh-3357-2022 | |
| dc.contributor.author | Kemik, Ozgur | |
| dc.contributor.author | Kemik, Ahu Sarbay | |
| dc.contributor.author | Sumer, Aziz | |
| dc.contributor.author | Begenik, Huseyin | |
| dc.contributor.author | Dulger, Ahmet Cumhur | |
| dc.contributor.author | Purisa, Sevim | |
| dc.contributor.author | Tuzun, Sefa | |
| dc.date.accessioned | 2025-05-10T16:48:25Z | |
| dc.date.available | 2025-05-10T16:48:25Z | |
| dc.date.issued | 2012 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Kemik, Ozgur; Sumer, Aziz] Yuzuncu Yil Univ, Tip Fak, Genel Cerrahi Klin, Dept Gen Surg, Van, Turkey; [Kemik, Ahu Sarbay] Istanbul Univ, Dept Biochem, Cerrahpasa Med Fac, Istanbul, Turkey; [Begenik, Huseyin] Yuzuncu Yil Univ, Dept Internal Med, Fac Med, Van, Turkey; [Dulger, Ahmet Cumhur] Yuzuncu Yil Univ, Dept Gastroenterol, Fac Med, Van, Turkey; [Purisa, Sevim] Istanbul Univ, Dept Biostat, Cerrahpasa Med Fac, Istanbul, Turkey; [Tuzun, Sefa] Haseki Training Hosp, Dept Gen Surg 2, Istanbul, Turkey | en_US |
| dc.description | Sumer, Aziz/0000-0003-3938-3363; Kemik, Ozgur/0000-0002-4612-1428 | en_US |
| dc.description.abstract | Background and objectives: To determine the serum levels of procarboxypeptidase A (pro-CPA) and carboxypeptidase A (CPA) in patients with acute and chronic pancreatitis and pancreatic cancer. Materials and methods: Serum samples obtained from 96 patients with acute pancreatitis, 101 patients with chronic pancreatitis, 98 patients with pancreatic cancer and 96 control groups were assayed for biochemical parameters and serum pro-CPA and CPA. Results: Serum pro-CPA and CPA levels were significantly higher in acute and in chronic pancreatic cancer patients compared to control group (p < 0.001). Pancreatic cancer patients had significantly higher serum pro-CPA and CPA levels when compared with acute and chronic pancreatitis cases (p < 0.001). Conclusion: These data prove for increased pro-CPA and CPA levels as a biomarker for the diagnosis of pancreatitis and pancreatic cancer. | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.doi | 10.1177/0960327111405864 | |
| dc.identifier.endpage | 451 | en_US |
| dc.identifier.issn | 0960-3271 | |
| dc.identifier.issue | 5 | en_US |
| dc.identifier.pmid | 21502183 | |
| dc.identifier.scopus | 2-s2.0-84864271805 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.startpage | 447 | en_US |
| dc.identifier.uri | https://doi.org/10.1177/0960327111405864 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/1530 | |
| dc.identifier.volume | 31 | en_US |
| dc.identifier.wos | WOS:000303552400003 | |
| dc.identifier.wosquality | Q3 | |
| dc.language.iso | en | en_US |
| dc.publisher | Sage Publications Ltd | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Procarboxypeptidase A | en_US |
| dc.subject | Carboxypeptidase A | en_US |
| dc.subject | Acute Pancreatitis | en_US |
| dc.subject | Chronic Pancreatitis | en_US |
| dc.subject | Pancreatic Cancer | en_US |
| dc.title | Serum Procarboxypeptidase a and Carboxypeptidase a Levels in Pancreatic Disease | en_US |
| dc.type | Article | en_US |