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Effects of Omethoate on Certain Oxidative Biomarkers in Various Tissues of Frogs (Rana Ridibunda) at Acute Exposure

dc.authorscopusid 54941365100
dc.authorscopusid 6507022732
dc.authorscopusid 8452071500
dc.authorwosid Çelik, İsmail/M-5085-2018
dc.contributor.author Isnas, Musa
dc.contributor.author Yegin, Esref
dc.contributor.author Celik, Ismail
dc.date.accessioned 2025-05-10T16:46:34Z
dc.date.available 2025-05-10T16:46:34Z
dc.date.issued 2012
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Isnas, Musa; Yegin, Esref; Celik, Ismail] Yuzuncu Yil Univ, Fac Sci, Dept Biol, TR-65080 Van, Turkey en_US
dc.description.abstract The study aimed mainly to assess effects of omethoate on certain oxidative stress biomarkers in various tissues of frogs (Rana ridibunda). Biomarkers selected for stress monitoring were malondialdehyde (MDA) and antioxidant defense system (ADS) constituent such as reduced glutathione (GSH) level, glutathione peroxidase (GSH-Px), glutathione-S-transferase (GST) and superoxide dismutase (SOD) activities in the liver, brain, heart and kidney tissues of frogs exposed to 10 and 20 ppm dosages of omethoate for 24, 48, 72 and 96 hours. Results showed that the administrations of omethoate promote MDA content in the tissues of the frogs treated with both dosages of omethoate. With regard to the ADS, GSH-Px, GST, SOD activities and GSH levels decreased after 24, 48, 72 and 96 hours in the tissues of treatment groups compared with controls. Collective results demonstrated that the exposures to omethoate of frogs induced an increase in MDA joined with fluctuated ADS. This may reflect the potential role of these parameters as useful biomarkers for assessment of aquatic pollution. en_US
dc.description.sponsorship University of Yuzuncu Yil Grant Commission [YYU-BAP-2009-FBE-YL005] en_US
dc.description.sponsorship The authors are grateful to the University of Yuzuncu Yil Grant Commission for providing financial assistance during the tenure of research numbered with YYU-BAP-2009-FBE-YL005. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1177/0748233711403191
dc.identifier.endpage 34 en_US
dc.identifier.issn 0748-2337
dc.identifier.issn 1477-0393
dc.identifier.issue 1 en_US
dc.identifier.pmid 22025503
dc.identifier.scopus 2-s2.0-84856410776
dc.identifier.scopusquality Q3
dc.identifier.startpage 27 en_US
dc.identifier.uri https://doi.org/10.1177/0748233711403191
dc.identifier.uri https://hdl.handle.net/20.500.14720/1195
dc.identifier.volume 28 en_US
dc.identifier.wos WOS:000299577400004
dc.identifier.wosquality Q4
dc.language.iso en en_US
dc.publisher Sage Publications inc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Rana Ridibunda en_US
dc.subject Omethoate en_US
dc.subject Antioxidant Defence Systems en_US
dc.subject Lipid Peroxidation en_US
dc.title Effects of Omethoate on Certain Oxidative Biomarkers in Various Tissues of Frogs (Rana Ridibunda) at Acute Exposure en_US
dc.type Article en_US

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