A Novel Screening Test for Esophageal Squamous Cell Carcinoma: Sirtuin-3
dc.authorid | Dulger, Cumhur/0000-0002-1844-7199 | |
dc.authorid | Kemik, Ozgur/0000-0002-4612-1428 | |
dc.authorscopusid | 6701581425 | |
dc.authorscopusid | 35483718900 | |
dc.authorscopusid | 6504566099 | |
dc.authorscopusid | 36774252500 | |
dc.authorscopusid | 6505748936 | |
dc.authorwosid | Kemik, Ozgur/Mgb-2153-2025 | |
dc.contributor.author | Cobanoglu, U. | |
dc.contributor.author | Dulger, C. | |
dc.contributor.author | Kemik, O. | |
dc.contributor.author | Celik, S. | |
dc.contributor.author | Sayir, F. | |
dc.date.accessioned | 2025-05-10T17:50:39Z | |
dc.date.available | 2025-05-10T17:50:39Z | |
dc.date.issued | 2017 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | [Cobanoglu, U.; Sayir, F.] Yuzuncu Yil Univ, Dept Thorac Surg, Van, Turkey; [Dulger, C.] Yuzuncu Yil Univ, Dept Gastroenterol, Van, Turkey; [Kemik, O.] Yuzuncu Yil Univ, Dept Surg Oncol, Van, Turkey; [Celik, S.] Yuzuncu Yil Univ, Dept Gen Surg, Van, Turkey | en_US |
dc.description | Dulger, Cumhur/0000-0002-1844-7199; Kemik, Ozgur/0000-0002-4612-1428 | en_US |
dc.description.abstract | OBJECTIVE: Human sirtuin-3, a protein involved in the mediation of tumors, has been shown to be present in malignancies. The goal of this study was to measure serum sirtuin-3 levels in esophageal squamous cancer cells and to determine whether sirtuin-3 may possess predictive value in advanced cases of esophageal squamous cell carcinoma (ESCC). PATIENTS AND METHODS: A total of 130 ESCC patients and 50 healthy control subjects participated to the study. Serum sirtuin-3 levels for all 180 subjects were measured using enzyme-linked immunosorbent assay (ELISA). RESULTS: Median sirtuin-3 levels were significantly higher in patients with ESCC than in the control subjects. CONCLUSIONS: The presence of considerably elevated levels of sirtuin-3, could be a powerful mediator of advanced ESCC in ESCC patients, suggests that sirtuin-3 may be a useful indicator of the disease. | en_US |
dc.description.woscitationindex | Science Citation Index Expanded | |
dc.identifier.endpage | 5401 | en_US |
dc.identifier.issn | 1128-3602 | |
dc.identifier.issue | 23 | en_US |
dc.identifier.pmid | 29243781 | |
dc.identifier.scopus | 2-s2.0-85042148641 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.startpage | 5399 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/17796 | |
dc.identifier.volume | 21 | en_US |
dc.identifier.wos | WOS:000419143200015 | |
dc.identifier.wosquality | Q2 | |
dc.language.iso | en | en_US |
dc.publisher | verduci Publisher | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Sirtuin-3 | en_US |
dc.subject | Screening | en_US |
dc.subject | Esophageal Cancer Escc | en_US |
dc.title | A Novel Screening Test for Esophageal Squamous Cell Carcinoma: Sirtuin-3 | en_US |
dc.type | Article | en_US |