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Detection and Sequence Analysis of Equine Gammaherpesviruses From Horses With Respiratory Tract Disease in Turkey

dc.authorid Tan, M. Tolga/0000-0001-5253-4010
dc.authorid Oguzoglu, Tuba Cigdem/0000-0003-4021-2414
dc.authorscopusid 56517110700
dc.authorscopusid 6506926572
dc.authorscopusid 6506646891
dc.authorscopusid 36984120700
dc.authorscopusid 15831622800
dc.authorscopusid 26023790300
dc.authorwosid Tan, Mehmet/H-1802-2012
dc.authorwosid Bilge Dagalp, Seval/Abe-5581-2021
dc.authorwosid Oguzoglu, Tuba Cigdem/V-5130-2018
dc.contributor.author Ataseven, V. S.
dc.contributor.author Bilge-Dagalp, S.
dc.contributor.author Oguzoglu, T. C.
dc.contributor.author Karapinar, Z.
dc.contributor.author Guzel, M.
dc.contributor.author Tan, M. T.
dc.date.accessioned 2025-05-10T16:49:26Z
dc.date.available 2025-05-10T16:49:26Z
dc.date.issued 2010
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Ataseven, V. S.] Mustafa Kemal Univ, Dept Virol, Fac Vet Med, TR-31040 Antakya, Hatay, Turkey; [Bilge-Dagalp, S.; Oguzoglu, T. C.] Ankara Univ, Dept Virol, Fac Vet Med, TR-06100 Ankara, Turkey; [Karapinar, Z.] Yuzuncu Yil Univ, Dept Virol, Fac Vet Med, Van, Turkey; [Guzel, M.] Mustafa Kemal Univ, Dept Internal Med, Fac Vet Med, TR-31040 Antakya, Hatay, Turkey; [Tan, M. T.] Adnan Menderes Univ, Dept Virol, Fac Vet Med, Aydin, Turkey en_US
dc.description Tan, M. Tolga/0000-0001-5253-4010; Oguzoglu, Tuba Cigdem/0000-0003-4021-2414 en_US
dc.description.abstract P>The equid herpesvirus 2 (EHV-2) and 5 (EHV-5), identified agents of respiratory infections and keratoconjunctivitis cases in some equids, comprise a high degree of antigenic heterogeneity. Prevalence and genetic characterization of EHV-2 and EHV-5 strains from Turkey were investigated in this study. A total of 73 nasal swabs and 54 blood specimens were sampled from horses with respiratory tract diseases characterized by mucopurulent nasal discharge and occasional coughing. Overall, EHV-2- and EHV-5-specific DNA amplicons were obtained from 19.2% (14/73) and 21.9% (16/73) of horses tested by multiplex nested PCR. Sequences of EHV-2 and EHV-5 glycoprotein B (gB) gene were used in a phylogenetic analysis that included six EHV-2 and three EHV-5 isolates, which showed that the Turkish EHV-2 and EHV-5 strains have marked sequence divergence from European strains and from each other. Turkish EHV-2 isolates were divided into two distinct subdivisions, and a few isolates were located on a separate branch. This study provides the first epidemiological and phylogenetical report about EHV-2 and EHV-5 infections in Turkey. en_US
dc.description.sponsorship Mustafa Kemal University, Hatay, TURKEY [08G-0202] en_US
dc.description.sponsorship We thank Dr Orhan Sahin at Iowa State University for his help in preparation of this manuscript. We also thank Dr Ilker ALTINTAS, DVM, for providing some of the blood samples used in this study. This project was supported by the Scientific Research Funds of Mustafa Kemal University, Hatay, TURKEY (contract no. 08G-0202). en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1111/j.1865-1682.2010.01146.x
dc.identifier.endpage 276 en_US
dc.identifier.issn 1865-1674
dc.identifier.issn 1865-1682
dc.identifier.issue 4 en_US
dc.identifier.pmid 20553426
dc.identifier.scopus 2-s2.0-77958137603
dc.identifier.scopusquality Q1
dc.identifier.startpage 271 en_US
dc.identifier.uri https://doi.org/10.1111/j.1865-1682.2010.01146.x
dc.identifier.uri https://hdl.handle.net/20.500.14720/1827
dc.identifier.volume 57 en_US
dc.identifier.wos WOS:000279620600008
dc.identifier.wosquality Q1
dc.language.iso en en_US
dc.publisher Wiley en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Equid Herpesvirus 2 en_US
dc.subject Equid Herpesvirus 5 en_US
dc.subject Mn-Pcr en_US
dc.subject Respiratory Disease en_US
dc.subject Sequencing en_US
dc.subject Turkey en_US
dc.title Detection and Sequence Analysis of Equine Gammaherpesviruses From Horses With Respiratory Tract Disease in Turkey en_US
dc.type Article en_US

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