YYÜ GCRIS Basic veritabanının içerik oluşturulması ve kurulumu Research Ecosystems (https://www.researchecosystems.com) tarafından devam etmektedir. Bu süreçte gördüğünüz verilerde eksikler olabilir.
 

Preoperative Serum Levels of Mesothelin in Patients With Colon Cancer

dc.authorid Yavuz, Alpaslan/0000-0002-8796-988X
dc.authorid Bostanci, Ozgur/0000-0002-6336-0420
dc.authorid Kemik, Ozgur/0000-0002-4612-1428
dc.authorscopusid 24330988400
dc.authorscopusid 6504566099
dc.authorscopusid 35332340400
dc.authorscopusid 23975576100
dc.authorscopusid 59152169100
dc.authorscopusid 6504310163
dc.authorscopusid 55682194900
dc.authorwosid Battal, Muharrem/Abh-9797-2020
dc.authorwosid Bostancı, Özgür/Aau-1546-2020
dc.authorwosid Kemik, Ozgur/Mgb-2153-2025
dc.authorwosid Yavuz, Alpaslan/H-3947-2014
dc.authorwosid Demir, Uygar/Abh-3172-2020
dc.authorwosid Yavuz, Alpaslan/E-2699-2014
dc.contributor.author Bostanci, Ozgur
dc.contributor.author Kemik, Ozgur
dc.contributor.author Kemik, Ahu
dc.contributor.author Battal, Muharrem
dc.contributor.author Demir, Uygar
dc.contributor.author Purisa, Sevim
dc.contributor.author Mihmanli, Mehmet
dc.date.accessioned 2025-05-10T17:45:36Z
dc.date.available 2025-05-10T17:45:36Z
dc.date.issued 2014
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Bostanci, Ozgur; Battal, Muharrem; Demir, Uygar; Mihmanli, Mehmet] Sisli Hamidiye Etfal Training & Res Hosp, Gen Surg Clin, Istanbul, Turkey; [Kemik, Ozgur] Yuzuncu Yil Univ, Dept Gen Surg, Fac Med, Van, Turkey; [Kemik, Ahu] Istanbul Univ, Dept Biochem, Cerrahpasa Med Fac, Istanbul, Turkey; [Purisa, Sevim] Istanbul Univ, Fac Med, Dept Biostat, Istanbul, Turkey; [Yavuz, Alpaslan] Yuzuncu Yil Univ, Fac Med, Dept Radiol, Van, Turkey en_US
dc.description Yavuz, Alpaslan/0000-0002-8796-988X; Bostanci, Ozgur/0000-0002-6336-0420; Kemik, Ozgur/0000-0002-4612-1428 en_US
dc.description.abstract Background. Screening for biochemical markers is important for diagnosing colon cancer. In this study, the reliability of serum mesothelin levels as a potential diagnostic and screening instrument was evaluated concerning colon cancer. Methods. Ninety-five patients who had undergone colonoscopic examination and who were diagnosed with colon cancer were included in the study. The serum mesothelin levels were measured with the ELISA kits and were evaluated in terms of significant difference when compared between colon cancer and control group. Results. Patients with colon cancer had significantly higher mesothelin serum levels (p<0.001) than the control groups. We found significant associations between serum levels and tumor grade, perineural invasion, and vascular invasion (resp., p<0.001). Conclusion. Evaluating the serum levels of mesothelin has a potential to detect and screen the colon cancer in affected patients. Our data suggest that mesothelin exhibits effects towards colon cancer and serves as a biomarker for this deadly disease. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1155/2014/161954
dc.identifier.issn 0278-0240
dc.identifier.issn 1875-8630
dc.identifier.pmid 25477701
dc.identifier.scopus 2-s2.0-84912144727
dc.identifier.scopusquality N/A
dc.identifier.uri https://doi.org/10.1155/2014/161954
dc.identifier.uri https://hdl.handle.net/20.500.14720/16403
dc.identifier.volume 2014 en_US
dc.identifier.wos WOS:000345559700001
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Hindawi Ltd en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.title Preoperative Serum Levels of Mesothelin in Patients With Colon Cancer en_US
dc.type Article en_US

Files