Preoperative Serum Levels of Mesothelin in Patients With Colon Cancer
dc.authorid | Yavuz, Alpaslan/0000-0002-8796-988X | |
dc.authorid | Bostanci, Ozgur/0000-0002-6336-0420 | |
dc.authorid | Kemik, Ozgur/0000-0002-4612-1428 | |
dc.authorscopusid | 24330988400 | |
dc.authorscopusid | 6504566099 | |
dc.authorscopusid | 35332340400 | |
dc.authorscopusid | 23975576100 | |
dc.authorscopusid | 59152169100 | |
dc.authorscopusid | 6504310163 | |
dc.authorscopusid | 55682194900 | |
dc.authorwosid | Battal, Muharrem/Abh-9797-2020 | |
dc.authorwosid | Bostancı, Özgür/Aau-1546-2020 | |
dc.authorwosid | Kemik, Ozgur/Mgb-2153-2025 | |
dc.authorwosid | Yavuz, Alpaslan/H-3947-2014 | |
dc.authorwosid | Demir, Uygar/Abh-3172-2020 | |
dc.authorwosid | Yavuz, Alpaslan/E-2699-2014 | |
dc.contributor.author | Bostanci, Ozgur | |
dc.contributor.author | Kemik, Ozgur | |
dc.contributor.author | Kemik, Ahu | |
dc.contributor.author | Battal, Muharrem | |
dc.contributor.author | Demir, Uygar | |
dc.contributor.author | Purisa, Sevim | |
dc.contributor.author | Mihmanli, Mehmet | |
dc.date.accessioned | 2025-05-10T17:45:36Z | |
dc.date.available | 2025-05-10T17:45:36Z | |
dc.date.issued | 2014 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | [Bostanci, Ozgur; Battal, Muharrem; Demir, Uygar; Mihmanli, Mehmet] Sisli Hamidiye Etfal Training & Res Hosp, Gen Surg Clin, Istanbul, Turkey; [Kemik, Ozgur] Yuzuncu Yil Univ, Dept Gen Surg, Fac Med, Van, Turkey; [Kemik, Ahu] Istanbul Univ, Dept Biochem, Cerrahpasa Med Fac, Istanbul, Turkey; [Purisa, Sevim] Istanbul Univ, Fac Med, Dept Biostat, Istanbul, Turkey; [Yavuz, Alpaslan] Yuzuncu Yil Univ, Fac Med, Dept Radiol, Van, Turkey | en_US |
dc.description | Yavuz, Alpaslan/0000-0002-8796-988X; Bostanci, Ozgur/0000-0002-6336-0420; Kemik, Ozgur/0000-0002-4612-1428 | en_US |
dc.description.abstract | Background. Screening for biochemical markers is important for diagnosing colon cancer. In this study, the reliability of serum mesothelin levels as a potential diagnostic and screening instrument was evaluated concerning colon cancer. Methods. Ninety-five patients who had undergone colonoscopic examination and who were diagnosed with colon cancer were included in the study. The serum mesothelin levels were measured with the ELISA kits and were evaluated in terms of significant difference when compared between colon cancer and control group. Results. Patients with colon cancer had significantly higher mesothelin serum levels (p<0.001) than the control groups. We found significant associations between serum levels and tumor grade, perineural invasion, and vascular invasion (resp., p<0.001). Conclusion. Evaluating the serum levels of mesothelin has a potential to detect and screen the colon cancer in affected patients. Our data suggest that mesothelin exhibits effects towards colon cancer and serves as a biomarker for this deadly disease. | en_US |
dc.description.woscitationindex | Science Citation Index Expanded | |
dc.identifier.doi | 10.1155/2014/161954 | |
dc.identifier.issn | 0278-0240 | |
dc.identifier.issn | 1875-8630 | |
dc.identifier.pmid | 25477701 | |
dc.identifier.scopus | 2-s2.0-84912144727 | |
dc.identifier.scopusquality | N/A | |
dc.identifier.uri | https://doi.org/10.1155/2014/161954 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/16403 | |
dc.identifier.volume | 2014 | en_US |
dc.identifier.wos | WOS:000345559700001 | |
dc.identifier.wosquality | N/A | |
dc.language.iso | en | en_US |
dc.publisher | Hindawi Ltd | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | Preoperative Serum Levels of Mesothelin in Patients With Colon Cancer | en_US |
dc.type | Article | en_US |