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Antidepressants and Menstruation Disorders in Women: a Cross-Sectional Study in Three Centers

dc.authorid Giynas Ayhan, Medine/0000-0002-7127-8929
dc.authorid Sengul, Cem/0000-0003-4067-6040
dc.authorid Selvi, Yavuz/0000-0003-0218-6796
dc.authorscopusid 12806313000
dc.authorscopusid 24170102500
dc.authorscopusid 55190880000
dc.authorscopusid 12791538700
dc.authorscopusid 55888057500
dc.authorscopusid 6603309359
dc.authorscopusid 55191358600
dc.authorwosid Selvi, Yavuz/Glt-0029-2022
dc.authorwosid Aşkın, Rüstem/Abc-3260-2020
dc.authorwosid Kose, Sukran/K-3936-2018
dc.authorwosid Sengul, Cem/Hji-7121-2023
dc.authorwosid Giynas Ayhan, Medine/O-3490-2018
dc.contributor.author Uguz, Faruk
dc.contributor.author Sahingoz, Mine
dc.contributor.author Kose, Seyit Ali
dc.contributor.author Ozbebit, Ozgur
dc.contributor.author Sengul, Cem
dc.contributor.author Selvi, Yavuz
dc.contributor.author Askin, Rustem
dc.date.accessioned 2025-05-10T16:48:40Z
dc.date.available 2025-05-10T16:48:40Z
dc.date.issued 2012
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Uguz, Faruk; Sahingoz, Mine; Ayhan, Medine Giynas; Dagistanli, Adnan; Askin, Rustem] Konya Univ, Meram Tip Fak, Psikiyatri Anabilim Dali, TR-42080 Akyokus, Konya, Turkey; [Kose, Seyit Ali] Duzce Univ, Fac Med, Dept Obstet & Gynecol, Duzce, Turkey; [Ozbebit, Ozgur] Van Ipekyolu State Hosp, Dept Psychiat, Van, Turkey; [Sengul, Cem] Pamukkale Univ, Fac Med, Dept Psychiat, Denizli, Turkey; [Selvi, Yavuz] Yuzuncu Yil Univ, Fac Med, Dept Psychiat, Van, Turkey; [Sengul, Ceyhan Balci] Denizli State Hosp, Dept Psychiat, Denizli, Turkey en_US
dc.description Giynas Ayhan, Medine/0000-0002-7127-8929; Sengul, Cem/0000-0003-4067-6040; Selvi, Yavuz/0000-0003-0218-6796 en_US
dc.description.abstract Objective: The relationship between menstruation disorders and antidepressant drugs usage in women remains unclear. In this study, we aimed to investigate the incidence rate of antidepressant-related menstruation disorders and to examine whether or not antidepressant use is associated with menstrual disorders in women. Methods: The study sample was gathered from three centers and four hospitals. A total of 1432 women who met the criteria of inclusion were included in the study. The sample was divided into two groups: the antidepressant group (n=793) and the control group (n=639). The menstruation disorders were established with reports from the study participants on the basis of related gynecological descriptions. Results: The prevalence of menstrual disorders was significantly higher in the antidepressant group (24.6%) than the control group (12.2%). The incidence of antidepressant-induced menstruation disorder was 14.5%. The antidepressants most associated with menstrual disorders were paroxetine, venlafaxine, sertraline and their combination with mirtazapine. Overall, the incidence rate was similar in women receiving selective serotonin reuptake inhibitors and serotonin noradrenaline reuptake inhibitors. Conclusions: The results of the present study suggest that menstruation disorders are frequently observed in women taking antidepressants and that it appears to be associated with antidepressant use at least in some women. (C) 2012 Elsevier Inc. All rights reserved. en_US
dc.description.woscitationindex Science Citation Index Expanded - Social Science Citation Index
dc.identifier.doi 10.1016/j.genhosppsych.2012.03.014
dc.identifier.endpage 533 en_US
dc.identifier.issn 0163-8343
dc.identifier.issn 1873-7714
dc.identifier.issue 5 en_US
dc.identifier.pmid 22534402
dc.identifier.scopus 2-s2.0-84865367677
dc.identifier.scopusquality Q1
dc.identifier.startpage 529 en_US
dc.identifier.uri https://doi.org/10.1016/j.genhosppsych.2012.03.014
dc.identifier.uri https://hdl.handle.net/20.500.14720/1608
dc.identifier.volume 34 en_US
dc.identifier.wos WOS:000308511500012
dc.identifier.wosquality Q1
dc.language.iso en en_US
dc.publisher Elsevier Science inc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.title Antidepressants and Menstruation Disorders in Women: a Cross-Sectional Study in Three Centers en_US
dc.type Article en_US

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