Potential Diagnostic and Prognostic Significance of Plasma Prolidase Activity in Gastric Cancer
| dc.authorid | Yilmaz, Ozkan/0000-0001-7320-0722 | |
| dc.authorscopusid | 36774252500 | |
| dc.authorscopusid | 24335444000 | |
| dc.authorscopusid | 56692252500 | |
| dc.authorscopusid | 55998916900 | |
| dc.authorscopusid | 56259656000 | |
| dc.contributor.author | Celik, Sebahattin | |
| dc.contributor.author | Kiziltan, Remzi | |
| dc.contributor.author | Yilmaz, Eyup M. | |
| dc.contributor.author | Yilmaz, Ozkan | |
| dc.contributor.author | Demir, Halit | |
| dc.date.accessioned | 2025-05-10T17:28:03Z | |
| dc.date.available | 2025-05-10T17:28:03Z | |
| dc.date.issued | 2017 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Celik, Sebahattin; Kiziltan, Remzi; Yilmaz, Ozkan] Yuzuncu Yil Univ, Dept Gen Surg, Fac Med, Van, Turkey; [Yilmaz, Eyup M.] Van Training & Educ Hosp, Dept Surg, Van, Turkey; [Demir, Halit] Yuzuncu Yil Univ, Dept Chem, Fac Sci & Art, Van, Turkey | en_US |
| dc.description | Yilmaz, Ozkan/0000-0001-7320-0722 | en_US |
| dc.description.abstract | Aim: Plasma prolidase activities (PPAs) in cases of gastric cancer. Methodology/results: This study was based on a prospective design. 60 patients with gastric cancer (operable cases: 48; inoperable: 12) and 60 healthy controls were included in the study. Prolidase activity was analyzed. The mean PPA levels in the operable, inoperable and control groups were 45.60 +/- 4.20, 54.35 +/- 4. 9 and 10.92 +/- 0.79 U/l, respectively (p < 0.001). PPA decreased significantly after tumor resection. PPA level was significant in differentiating operable cases from inoperable (sensitivity: 91.7%; specificity: 85.2%). Discussion/conclusion: PPA was significantly higher in patients with inoperable gastric cancer than in operable cases and the control group. A strong correlation was found between tumor volume and PPA. | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.doi | 10.2217/bmm-2016-0367 | |
| dc.identifier.endpage | 327 | en_US |
| dc.identifier.issn | 1752-0363 | |
| dc.identifier.issn | 1752-0371 | |
| dc.identifier.issue | 4 | en_US |
| dc.identifier.pmid | 28150509 | |
| dc.identifier.scopus | 2-s2.0-85016758520 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 319 | en_US |
| dc.identifier.uri | https://doi.org/10.2217/bmm-2016-0367 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/11924 | |
| dc.identifier.volume | 11 | en_US |
| dc.identifier.wos | WOS:000401945400003 | |
| dc.identifier.wosquality | Q4 | |
| dc.language.iso | en | en_US |
| dc.publisher | Future Medicine Ltd | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Enzymes | en_US |
| dc.subject | Gastric Cancer | en_US |
| dc.subject | Prognostic Factors | en_US |
| dc.subject | Prolidase Activity | en_US |
| dc.subject | Tumor Markers | en_US |
| dc.title | Potential Diagnostic and Prognostic Significance of Plasma Prolidase Activity in Gastric Cancer | en_US |
| dc.type | Article | en_US |