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The Effect of Gingko Biloba Extract (Egb 761) as a Free Radical Scavenger on the Survival of Skin Flaps in Rats -: a Comparative Study

dc.authorid Ozyazgan, Irfan/0000-0003-2074-4587
dc.authorscopusid 6701914821
dc.authorscopusid 56006411800
dc.authorscopusid 35579240900
dc.authorwosid Ozyazgan, Irfan/U-6431-2018
dc.contributor.author Bekerecioglu, M
dc.contributor.author Tercan, M
dc.contributor.author Özyazgan, I
dc.date.accessioned 2025-05-10T17:13:22Z
dc.date.available 2025-05-10T17:13:22Z
dc.date.issued 1998
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp Yuzuncu Yil Univ, Fac Med, Dept Plast & Reconstruct Surg, TR-65200 Van, Turkey; Alparslan Mah Farabi Cad 23 22, Kayseri, Turkey; Millet Cad Bakkaloglu Is Mrk, Kayseri, Turkey en_US
dc.description Ozyazgan, Irfan/0000-0003-2074-4587 en_US
dc.description.abstract Free radicals may have a role in pedicle flap necrosis. We undertook this study to compare the effect of various antioxidants and scavengers of free radicals such as vitamin E, vitamin C, deferoxamine, and Gingko biloba extract (Egb 761) on McFarlane caudal-based dorsal rat flaps. Fifty rats were divided into five groups of 10 animals each. One group served as a control (saline) group. The remaining four groups were given vitamin C 340 mg/kg, deferoxamine 150 mg/kg, Egb 761 100 mg/kg, and vitamin E 20 mg/kg. The necrosed area of flap was significantly reduced in the deferoxamine (p < 0.001), Egb 761 (p < 0.001), and vitamin C (p < 0.05) groups compared with the control group. Vitamin E had no effect on distal flap necrosis (p = 0.20). en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1080/02844319850158741
dc.identifier.endpage 139 en_US
dc.identifier.issn 0284-4311
dc.identifier.issue 2 en_US
dc.identifier.pmid 9646361
dc.identifier.scopus 2-s2.0-0031778886
dc.identifier.scopusquality N/A
dc.identifier.startpage 135 en_US
dc.identifier.uri https://doi.org/10.1080/02844319850158741
dc.identifier.uri https://hdl.handle.net/20.500.14720/8175
dc.identifier.volume 32 en_US
dc.identifier.wos WOS:000074142300002
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Scandinavian University Press en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Gingko Biloba Extract (Egb 761) en_US
dc.subject Pedicle Skin Flap en_US
dc.subject Free Radicals en_US
dc.title The Effect of Gingko Biloba Extract (Egb 761) as a Free Radical Scavenger on the Survival of Skin Flaps in Rats -: a Comparative Study en_US
dc.type Article en_US

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