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The Electrophoretical Determination of Serum Protein Fractions in Lycopene Treated Experimental Diabetic Rats

dc.authorid Dede, Semiha/0000-0001-5744-6327
dc.authorid Ceylan, Ebubekir/0000-0002-3993-3145
dc.authorscopusid 55736672600
dc.authorscopusid 6603709171
dc.authorscopusid 7004664599
dc.authorwosid Ceylan, Ebubekir/Hhm-5886-2022
dc.authorwosid Dede, Semiha/H-5403-2013
dc.authorwosid Ceylan, Ebubekir/N-8597-2015
dc.contributor.author Yuksek, Veysel
dc.contributor.author Dede, Semiha
dc.contributor.author Ceylan, Ebubekir
dc.date.accessioned 2025-05-10T17:45:52Z
dc.date.available 2025-05-10T17:45:52Z
dc.date.issued 2013
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Yuksek, Veysel; Dede, Semiha] Yuzuncu Yil Univ, Sch Vet Med, Dept Biochem, TR-65080 Van, Turkey; [Ceylan, Ebubekir] Yuzuncu Yil Univ, Sch Vet Med, Internal Dis Dept, TR-65080 Van, Turkey en_US
dc.description Dede, Semiha/0000-0001-5744-6327; Ceylan, Ebubekir/0000-0002-3993-3145 en_US
dc.description.abstract This study was planned to determine the effects of lycopene treatment on serum protein fractions in experimental diabetic rats. In order to induce diabetes in rats in the diabetes (D) and diabetes + lycopene (DL) groups, rats were given 45 mg/kg single-dose streptozotocin intraperitoneally. Lycopene (10 mg/kg/day dissolved in sunflower oil) was administered to the rats in the lycopene-only (L) and DL groups. Blood glucose levels and HbA1c% in DL group and diabetes group increased (p < 0.05) compared to control and L group. Total protein, albumin, alpha(1), alpha(2), and beta globulin fractions of diabetic and DL groups were lower than control and L groups (p < 0.05). D group had lowest gamma (gamma) globulin levels among other groups (p < 0.05). The gamma globulin levels was slightly increased than diabetic groups (D and DL), but it was still lower than control and L groups (p < 0.05). The highest value of A/G ratio was observed in diabetic group. Similarly, the % level of A/G ratio of D group was higher than other groups. It was noted that the A/G ratio decreased and reached to control group levels after lycopene treatment. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1007/s12013-013-9660-2
dc.identifier.endpage 1289 en_US
dc.identifier.issn 1085-9195
dc.identifier.issn 1559-0283
dc.identifier.issue 3 en_US
dc.identifier.pmid 23712872
dc.identifier.scopus 2-s2.0-84888311711
dc.identifier.scopusquality Q3
dc.identifier.startpage 1283 en_US
dc.identifier.uri https://doi.org/10.1007/s12013-013-9660-2
dc.identifier.uri https://hdl.handle.net/20.500.14720/16487
dc.identifier.volume 67 en_US
dc.identifier.wos WOS:000327455400053
dc.identifier.wosquality Q3
dc.language.iso en en_US
dc.publisher Humana Press inc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Diabetes Mellitus en_US
dc.subject Serum Protein Fractions en_US
dc.subject Lycopene en_US
dc.subject Hba1C en_US
dc.subject Rats en_US
dc.subject Stz en_US
dc.title The Electrophoretical Determination of Serum Protein Fractions in Lycopene Treated Experimental Diabetic Rats en_US
dc.type Article en_US

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