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Increased Nuchal Translucency and Pregnancy Outcomes: a Tertiary Center Data

dc.authorid Karaaslan, Onur/0000-0002-4599-1173
dc.authorscopusid 6505945892
dc.authorscopusid 57200143199
dc.authorscopusid 26027617800
dc.authorscopusid 57203359912
dc.authorscopusid 42262158200
dc.authorwosid Karaman, Erbil/Afu-7129-2022
dc.contributor.author Bagci, Mustafa
dc.contributor.author Uckan, Kazim
dc.contributor.author Sahin, Hanim Guler
dc.contributor.author Karaaslan, Onur
dc.contributor.author Karaman, Erbil
dc.date.accessioned 2025-05-10T17:23:47Z
dc.date.available 2025-05-10T17:23:47Z
dc.date.issued 2024
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Bagci, Mustafa; Uckan, Kazim; Sahin, Hanim Guler] Van Yuzuncu Yil Univ, Fac Med, Dept Obstet & Gynecol, Perinatol Div, Van, Turkiye; [Karaaslan, Onur] Van Yuzuncu Yil Univ, Fac Med, Dept Gynecol & Obstet, Van, Turkiye; [Karaman, Erbil] Van Yuzuncu Yil Univ, Fac Med, Gynecol Oncol Div, Dept Gynecol & Obstet, Van, Turkiye en_US
dc.description Karaaslan, Onur/0000-0002-4599-1173 en_US
dc.description.abstract Aim: This study aimed to evaluate the pregnancy outcomes of patients who applied to our clinic between the 11th and 14th weeks of pregnancy and whose nuchal translucency (NT) measurement was >= 1.5 multiples of the median (MoM). Material and Methods: The study included 85 patients whose NT measurement was determined >= 1.5 MoM and pregnancy results were available. Demographic characteristics of the patients, prenatal invasive diagnostic test results, fetal anomaly screening, fetal echocardiography (ECHO) results, and neonatal and obstetric results were evaluated. Results: Abnormal karyotype was detected in 10.6% (n=9) of the patients. Trisomy 21 was the most common chromosomal anomaly. Fetal structural anomaly was detected in 29.4% (n=25) of the patients. A structural fetal anomaly was detected in 21% (n=13) of fetuses with normal karyotypes and 66.7% (n=6) of fetuses with abnormal karyotypes. Cardiac anomalies were found to be the most common anomalies with 9.7% (n=6) in patients with normal karyotype. NT and NT MoM values in patients with fetal structural (both p=0.001) or chromosomal anomalies (p=0.011, and p=0.019, respectively) were found significantly higher than those without. NT and NT MoM values in patients whose pregnancies resulted in fetal loss were found significantly higher than in patients who had a live birth (both p=0.001). Conclusion: Increasing NT or NT MoM values indicate an increase in the risk of chromosomal anomalies, structural anomalies, and poor pregnancy outcomes in the fetus. Fetal anomaly screening and fetal ECHO should be recommended in patients with increased NT, even if a normal karyotype is detected. en_US
dc.description.woscitationindex Emerging Sources Citation Index
dc.identifier.doi 10.18678/dtfd.1410977
dc.identifier.endpage 43 en_US
dc.identifier.issn 1307-671X
dc.identifier.issue 1 en_US
dc.identifier.scopus 2-s2.0-85192496334
dc.identifier.scopusquality Q3
dc.identifier.startpage 38 en_US
dc.identifier.uri https://doi.org/10.18678/dtfd.1410977
dc.identifier.uri https://hdl.handle.net/20.500.14720/11000
dc.identifier.volume 26 en_US
dc.identifier.wos WOS:001260510700006
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Duzce Univ, Fac Medicine en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Abnormal Karyotype en_US
dc.subject Anomaly en_US
dc.subject Increased Nuchal Translucency en_US
dc.title Increased Nuchal Translucency and Pregnancy Outcomes: a Tertiary Center Data en_US
dc.type Article en_US

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