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Preoperative Levels of Matrix Metalloproteinase-7 And-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 Relation To Pathologic Parameters in Bladder Carcinoma Patients

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dc.authorid Yuksel, Mehmet Bilgehan/0000-0002-5968-7981
dc.authorid Gunes, Mustafa/0000-0003-2044-9086
dc.authorscopusid 35769316200
dc.authorscopusid 35332340400
dc.authorscopusid 9244561200
dc.authorscopusid 8720316900
dc.authorscopusid 36524209300
dc.authorscopusid 36931806600
dc.authorscopusid 24334938700
dc.authorwosid Pirincci, Necip/W-7637-2018
dc.authorwosid Yuksel, Mehmet/H-5207-2019
dc.authorwosid Geçit, İlhan/Abi-8258-2020
dc.authorwosid Gunes, Mustafa/Aar-9915-2020
dc.contributor.author Gunes, Mustafa
dc.contributor.author Kemik, Ahu Serap
dc.contributor.author Pirincci, Necip
dc.contributor.author Gecit, Ilhan
dc.contributor.author Taken, Kerem
dc.contributor.author Yuksel, Mehmet Bilgehan
dc.contributor.author Eryilmaz, Recep
dc.date.accessioned 2025-05-10T16:48:11Z
dc.date.available 2025-05-10T16:48:11Z
dc.date.issued 2013
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Gunes, Mustafa; Pirincci, Necip; Gecit, Ilhan; Eryilmaz, Recep] Yuzuncu Yil Univ, Fac Med, Dept Urol, Van, Turkey; [Taken, Kerem; Kaba, Mehmet] Van State Hosp, Urol Clin, Van, Turkey; [Kemik, Ahu Serap] Istanbul Univ, Cerrahpasa Med Fac, Dept Biochem, Istanbul, Turkey; [Yuksel, Mehmet Bilgehan] Celal Bayar Univ, Fac Med, Dept Urol, Manisa, Turkey en_US
dc.description Yuksel, Mehmet Bilgehan/0000-0002-5968-7981; Gunes, Mustafa/0000-0003-2044-9086 en_US
dc.description.abstract Our aim was to test the hypothesis that preoperative serum levels of matrix metalloproteinase-7 (MMP-7) and -9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) levels correlate with pathological features. Serum levels of MMP-7, and MMP-9 and TIMP-1 were determined in 90 bladder cancer patients and 40 healthy controls using an enzyme linked immunosorbent assay. Preoperative serum MMP-7 and MMP-9 levels were significantly higher in cancer patients than control groups (p<0.001). In contast, serum TIMP-1 levels were lower (p<0.001). Alteration in MMP-7, and MMP-9, and TIMP-1 production may contribute to tumor angiogenesis and be associated with clinic-pathological features. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.7314/APJCP.2013.14.2.873
dc.identifier.endpage 876 en_US
dc.identifier.issn 1513-7368
dc.identifier.issue 2 en_US
dc.identifier.pmid 23621254
dc.identifier.scopus 2-s2.0-84877652965
dc.identifier.scopusquality Q3
dc.identifier.startpage 873 en_US
dc.identifier.uri https://doi.org/10.7314/APJCP.2013.14.2.873
dc.identifier.uri https://hdl.handle.net/20.500.14720/1480
dc.identifier.volume 14 en_US
dc.identifier.wos WOS:000324920000048
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Asian Pacific Organization Cancer Prevention en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Mmp-7 en_US
dc.subject Mmp-9 en_US
dc.subject Timp-1 en_US
dc.subject Bladder Cancer en_US
dc.subject Pathological Parameters en_US
dc.title Preoperative Levels of Matrix Metalloproteinase-7 And-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 Relation To Pathologic Parameters in Bladder Carcinoma Patients en_US
dc.type Article en_US

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