Plantago Major Protective Effects on Antioxidant Status After Administration of 7,12-Dimethylbenz(a)anthracene in Rats
| dc.authorid | Yasar, Semih/0000-0003-2754-6030 | |
| dc.authorid | Yasar, Semih/0000-0002-2149-405X | |
| dc.authorid | Ekin, Suat/0000-0002-6502-5028 | |
| dc.authorid | Ozdemir, Hulya/0000-0002-6045-8342 | |
| dc.authorid | Levent, Abdulkadir/0000-0001-5792-419X | |
| dc.authorscopusid | 25230277800 | |
| dc.authorscopusid | 6602257873 | |
| dc.authorscopusid | 7004290487 | |
| dc.authorscopusid | 56259656000 | |
| dc.authorscopusid | 23471490500 | |
| dc.authorscopusid | 6602133530 | |
| dc.authorscopusid | 6602615713 | |
| dc.authorwosid | Kaki, Baris/K-7470-2012 | |
| dc.authorwosid | Yaåÿar, Semih/V-6402-2019 | |
| dc.authorwosid | Ekin, Suat/Aar-2193-2020 | |
| dc.authorwosid | Levent, Abdulkadir/V-5418-2017 | |
| dc.contributor.author | Oto, Gokhan | |
| dc.contributor.author | Ekin, Suat | |
| dc.contributor.author | Ozdemir, Hulya | |
| dc.contributor.author | Demir, Halit | |
| dc.contributor.author | Yasar, Semih | |
| dc.contributor.author | Levent, Abdulkadir | |
| dc.contributor.author | Kaki, Baris | |
| dc.date.accessioned | 2025-05-10T17:48:36Z | |
| dc.date.available | 2025-05-10T17:48:36Z | |
| dc.date.issued | 2011 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Oto, Gokhan; Ozdemir, Hulya] Yuzuncu Yil Univ, Fac Med, Dept Pharmacol, Van, Turkey; [Ekin, Suat; Demir, Halit] Yuzuncu Yil Univ, Fac Sci, Dept Biochem, Van, Turkey; [Kaki, Baris] Yuzuncu Yil Univ, Fac Agr, Dept Biometry & Genet, Van, Turkey; [Yasar, Semih] Bingol Univ, Fac Arts & Sci, Dept Biochem, Bingoll, Turkey; [Levent, Abdulkadir] Batman Univ, Fac Arts & Sci, Dept Analyt Chem, Batman, Turkey; [Berber, Ismet] Sinop Univ, Fac Arts & Sci, Dept Biol, Sinop, Turkey | en_US |
| dc.description | Yasar, Semih/0000-0003-2754-6030; Yasar, Semih/0000-0002-2149-405X; Ekin, Suat/0000-0002-6502-5028; Ozdemir, Hulya/0000-0002-6045-8342; Levent, Abdulkadir/0000-0001-5792-419X | en_US |
| dc.description.abstract | Aim: The present study was designed to evaluate effects of Plantago major extract on oxidative status in Wistar albino rats administrated 7,12-dimethylbenz(a)anthracene (DMBA). Methods: Rats were divided into three equal groups of 6 animals each: Group 1 controls, group 2 treated with DMBA (100 mg/kg, single dose) and group 3 receiving the DMBA and the aqueous extract at 100 mg/kg/d for 60 days. Results: Significant decrease in catalase (P<0.05), carbonic anhydrase (p <= 0.01), reduced glutathione (GSH) (P<0.01) and total protein (P<0.01) values was observed in the DMBA group compared with the healthy controls and DMBA + Plantago major groups. Conclusion: The results suggest preventive effects of Plantago major on DMBA induced oxidative damage in Wistar albino rats that might be due to decreased free radical generation. | en_US |
| dc.description.sponsorship | Presidency of Yuzuncu Yil University [2008-FED-B083] | en_US |
| dc.description.sponsorship | This study was supported by a grant from the Scientific Research Projects Presidency of Yuzuncu Yil University (2008-FED-B083). | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.endpage | 535 | en_US |
| dc.identifier.issn | 1513-7368 | |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.pmid | 21545225 | |
| dc.identifier.scopus | 2-s2.0-79958782513 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 531 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/17169 | |
| dc.identifier.volume | 12 | en_US |
| dc.identifier.wos | WOS:000293172800035 | |
| dc.identifier.wosquality | N/A | |
| dc.language.iso | en | en_US |
| dc.publisher | Asian Pacific Organization Cancer Prevention | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Antioxidant | en_US |
| dc.subject | Dmba | en_US |
| dc.subject | Lipid Peroxidation | en_US |
| dc.subject | Plantago Major | en_US |
| dc.subject | Rat | en_US |
| dc.title | Plantago Major Protective Effects on Antioxidant Status After Administration of 7,12-Dimethylbenz(a)anthracene in Rats | en_US |
| dc.type | Article | en_US |