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Plantago Major Protective Effects on Antioxidant Status After Administration of 7,12-Dimethylbenz(a)anthracene in Rats

dc.authorid Yasar, Semih/0000-0003-2754-6030
dc.authorid Yasar, Semih/0000-0002-2149-405X
dc.authorid Ekin, Suat/0000-0002-6502-5028
dc.authorid Ozdemir, Hulya/0000-0002-6045-8342
dc.authorid Levent, Abdulkadir/0000-0001-5792-419X
dc.authorscopusid 25230277800
dc.authorscopusid 6602257873
dc.authorscopusid 7004290487
dc.authorscopusid 56259656000
dc.authorscopusid 23471490500
dc.authorscopusid 6602133530
dc.authorscopusid 6602615713
dc.authorwosid Kaki, Baris/K-7470-2012
dc.authorwosid Yaåÿar, Semih/V-6402-2019
dc.authorwosid Ekin, Suat/Aar-2193-2020
dc.authorwosid Levent, Abdulkadir/V-5418-2017
dc.contributor.author Oto, Gokhan
dc.contributor.author Ekin, Suat
dc.contributor.author Ozdemir, Hulya
dc.contributor.author Demir, Halit
dc.contributor.author Yasar, Semih
dc.contributor.author Levent, Abdulkadir
dc.contributor.author Kaki, Baris
dc.date.accessioned 2025-05-10T17:48:36Z
dc.date.available 2025-05-10T17:48:36Z
dc.date.issued 2011
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Oto, Gokhan; Ozdemir, Hulya] Yuzuncu Yil Univ, Fac Med, Dept Pharmacol, Van, Turkey; [Ekin, Suat; Demir, Halit] Yuzuncu Yil Univ, Fac Sci, Dept Biochem, Van, Turkey; [Kaki, Baris] Yuzuncu Yil Univ, Fac Agr, Dept Biometry & Genet, Van, Turkey; [Yasar, Semih] Bingol Univ, Fac Arts & Sci, Dept Biochem, Bingoll, Turkey; [Levent, Abdulkadir] Batman Univ, Fac Arts & Sci, Dept Analyt Chem, Batman, Turkey; [Berber, Ismet] Sinop Univ, Fac Arts & Sci, Dept Biol, Sinop, Turkey en_US
dc.description Yasar, Semih/0000-0003-2754-6030; Yasar, Semih/0000-0002-2149-405X; Ekin, Suat/0000-0002-6502-5028; Ozdemir, Hulya/0000-0002-6045-8342; Levent, Abdulkadir/0000-0001-5792-419X en_US
dc.description.abstract Aim: The present study was designed to evaluate effects of Plantago major extract on oxidative status in Wistar albino rats administrated 7,12-dimethylbenz(a)anthracene (DMBA). Methods: Rats were divided into three equal groups of 6 animals each: Group 1 controls, group 2 treated with DMBA (100 mg/kg, single dose) and group 3 receiving the DMBA and the aqueous extract at 100 mg/kg/d for 60 days. Results: Significant decrease in catalase (P<0.05), carbonic anhydrase (p <= 0.01), reduced glutathione (GSH) (P<0.01) and total protein (P<0.01) values was observed in the DMBA group compared with the healthy controls and DMBA + Plantago major groups. Conclusion: The results suggest preventive effects of Plantago major on DMBA induced oxidative damage in Wistar albino rats that might be due to decreased free radical generation. en_US
dc.description.sponsorship Presidency of Yuzuncu Yil University [2008-FED-B083] en_US
dc.description.sponsorship This study was supported by a grant from the Scientific Research Projects Presidency of Yuzuncu Yil University (2008-FED-B083). en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.endpage 535 en_US
dc.identifier.issn 1513-7368
dc.identifier.issue 2 en_US
dc.identifier.pmid 21545225
dc.identifier.scopus 2-s2.0-79958782513
dc.identifier.scopusquality Q3
dc.identifier.startpage 531 en_US
dc.identifier.uri https://hdl.handle.net/20.500.14720/17169
dc.identifier.volume 12 en_US
dc.identifier.wos WOS:000293172800035
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Asian Pacific Organization Cancer Prevention en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Antioxidant en_US
dc.subject Dmba en_US
dc.subject Lipid Peroxidation en_US
dc.subject Plantago Major en_US
dc.subject Rat en_US
dc.title Plantago Major Protective Effects on Antioxidant Status After Administration of 7,12-Dimethylbenz(a)anthracene in Rats en_US
dc.type Article en_US

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