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Evaluation of Lymphocyte Subgroups in Children With Down Syndrome

dc.authorid Bala, Keziban Asli/0000-0001-8755-7714
dc.authorscopusid 56736815700
dc.authorscopusid 14526773500
dc.authorscopusid 36055987800
dc.authorscopusid 56736778900
dc.authorscopusid 6506372343
dc.authorscopusid 57189220861
dc.authorscopusid 26531350600
dc.authorwosid Kaya, Avni/O-6540-2014
dc.authorwosid Bala, Keziban Aslı/Meo-8657-2025
dc.authorwosid Bala, Keziban Asli/H-1307-2019
dc.contributor.author Yilmaz, Cahide
dc.contributor.author Dogan, Murat
dc.contributor.author Basarslan, Fatmagul
dc.contributor.author Yilmaz, Nebi
dc.contributor.author Yuca, Sevil
dc.contributor.author Bulan, Keziban
dc.contributor.author Caksen, Huseyin
dc.date.accessioned 2025-05-10T17:11:54Z
dc.date.available 2025-05-10T17:11:54Z
dc.date.issued 2015
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Yilmaz, Cahide; Yilmaz, Nebi] Yildirim Beyazit Univ, Sch Med, Dept Pediat, Ankara, Turkey; [Dogan, Murat; Bulan, Keziban] Yuzuncu Yil Univ, Sch Med, Dept Pediat, TR-65100 Van, Turkey; [Basarslan, Fatmagul] Mustafa Kemal Univ, Sch Med, Dept Pediat, Antakya, Turkey; [Yuca, Sevil] Selcuk Univ, Sch Med, Dept Pediat, Konya, Turkey; [Kaya, Avni] Ataturk Univ, Sch Med, Dept Pediat, Van, Turkey; [Caksen, Huseyin] Necmettin Erbakan Univ, Sch Med, Dept Pediat, Konya, Turkey en_US
dc.description Bala, Keziban Asli/0000-0001-8755-7714 en_US
dc.description.abstract In this study, lymphocyte subgroups including blood CD3, CD4, CD8, CD4/CD8, CD19, and CD16.56 values were analyzed in children with Down syndrome (DS). The study includes 85 children with DS, followed at Department of Pediatrics, Faculty of Medicine, Yuzuncu Yil University and 64 healthy age-matched control participants. Blood CD3, CD4, CD8, CD4/CD8, CD19, and CD16.56 values were examined in both the groups. Significantly decreased blood CD3, CD4, and CD19 values were found in the study group (P < .05) when compared with the control group. In conclusion, we would like to emphasize that blood CD3, CD4, and CD19 levels were found to be decreased in children with DS. Based on these finding, we think that these decreased lymphocyte subgroups might be responsible for increased susceptibility to infections in children with DS. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1177/1076029613511521
dc.identifier.endpage 549 en_US
dc.identifier.issn 1076-0296
dc.identifier.issn 1938-2723
dc.identifier.issue 6 en_US
dc.identifier.pmid 24243939
dc.identifier.scopus 2-s2.0-84937835925
dc.identifier.scopusquality Q2
dc.identifier.startpage 546 en_US
dc.identifier.uri https://doi.org/10.1177/1076029613511521
dc.identifier.uri https://hdl.handle.net/20.500.14720/7737
dc.identifier.volume 21 en_US
dc.identifier.wos WOS:000358581300007
dc.identifier.wosquality Q2
dc.language.iso en en_US
dc.publisher Sage Publications inc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Down Syndrome en_US
dc.subject Lymphocyte Subgroups en_US
dc.subject Cd en_US
dc.title Evaluation of Lymphocyte Subgroups in Children With Down Syndrome en_US
dc.type Article en_US

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