Effect of Crush and Axotomy of Phrenic Nerves on Oxidative Stress in Diaphragm Muscle of Rats
dc.authorscopusid | 6505748936 | |
dc.authorscopusid | 23097741000 | |
dc.authorscopusid | 7003988714 | |
dc.authorscopusid | 56259656000 | |
dc.authorscopusid | 55391495500 | |
dc.authorscopusid | 6701581425 | |
dc.authorwosid | Meral, Ismail/O-7139-2019 | |
dc.authorwosid | Cengiz, Nureddin/A-4949-2018 | |
dc.authorwosid | Kavak, Servet/Abb-6429-2020 | |
dc.contributor.author | Sayir, Fuat | |
dc.contributor.author | Kavak, Servet | |
dc.contributor.author | Meral, Ismail | |
dc.contributor.author | Demir, Halit | |
dc.contributor.author | Cengiz, Nurettin | |
dc.contributor.author | Cobanoglu, Ufuk | |
dc.date.accessioned | 2025-05-10T16:46:37Z | |
dc.date.available | 2025-05-10T16:46:37Z | |
dc.date.issued | 2012 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | [Sayir, Fuat; Cobanoglu, Ufuk] Yuzuncu Yil Univ, Fac Med, Dept Thorac Surg, TR-65100 Van, Turkey; [Kavak, Servet] Yuzuncu Yil Univ, Fac Med, Dept Biophys, TR-65100 Van, Turkey; [Meral, Ismail] Yuzuncu Yil Univ, Fac Med, Dept Physiol, TR-65100 Van, Turkey; [Demir, Halit] Yuzuncu Yil Univ, Fac Sci, Div Biochem, Dept Chem, TR-65100 Van, Turkey; [Cengiz, Nurettin] Yuzuncu Yil Univ, Fac Sci, Dept Histol & Embryol, TR-65100 Van, Turkey | en_US |
dc.description.abstract | Introduction: In this study we investigated the effect of crush and axotomy of phrenic nerves on oxidative stress and antioxidant enzyme activities in rat diaphragm muscle. Methods: The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Results: The malondialdehyde level increased in diaphragm muscles after both crush and axotomy. The antioxidant enzymes, such as superoxide dismutase, glutathione peroxidase, carbonic anhydrase, and catalase, decreased in diaphragm muscles after both crush and axotomy. Conclusions: Crushing or axotomizing the phrenic nerves may produce oxidative stress in the diaphragm muscle of the rat by increasing lipid peroxidation and decreasing antioxidant enzyme activities. Muscle Nerve, 2012 | en_US |
dc.description.woscitationindex | Science Citation Index Expanded | |
dc.identifier.doi | 10.1002/mus.22312 | |
dc.identifier.endpage | 415 | en_US |
dc.identifier.issn | 0148-639X | |
dc.identifier.issn | 1097-4598 | |
dc.identifier.issue | 3 | en_US |
dc.identifier.pmid | 22334176 | |
dc.identifier.scopus | 2-s2.0-84857067625 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.startpage | 412 | en_US |
dc.identifier.uri | https://doi.org/10.1002/mus.22312 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/1209 | |
dc.identifier.volume | 45 | en_US |
dc.identifier.wos | WOS:000300684600013 | |
dc.identifier.wosquality | Q2 | |
dc.language.iso | en | en_US |
dc.publisher | Wiley | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Antioxidant Enzyme | en_US |
dc.subject | Diaphragm Muscle | en_US |
dc.subject | Oxidative Stress | en_US |
dc.subject | Phrenic Nerve Degeneration | en_US |
dc.subject | Rat | en_US |
dc.title | Effect of Crush and Axotomy of Phrenic Nerves on Oxidative Stress in Diaphragm Muscle of Rats | en_US |
dc.type | Article | en_US |