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A Novel Echocardiographic Method for Assessing Arterial Stiffness in Obstructive Sleep Apnea Syndrome

dc.authorid Gumrukcuoglu, Hasan Ali/0000-0002-5972-9870
dc.authorscopusid 24480843500
dc.authorscopusid 15051580600
dc.authorscopusid 36522223300
dc.authorscopusid 54406819200
dc.authorscopusid 6507138719
dc.authorscopusid 56957185000
dc.authorscopusid 57192065932
dc.authorwosid Yaman, Mehmet/Lxa-8177-2024
dc.contributor.author Akdag, Serkan
dc.contributor.author Akyol, Aytac
dc.contributor.author Cakmak, Huseyin Altug
dc.contributor.author Gunbatar, Hulya
dc.contributor.author Asker, Muntecep
dc.contributor.author Babat, Naci
dc.contributor.author Gumrukcuoglu, Hasan Ali
dc.date.accessioned 2025-05-10T17:39:56Z
dc.date.available 2025-05-10T17:39:56Z
dc.date.issued 2015
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Akdag, Serkan; Akyol, Aytac; Asker, Muntecep; Babat, Naci; Gumrukcuoglu, Hasan Ali] Yuzuncu Yil Univ, Fac Med, Dept Cardiol, TR-65100 Van, Turkey; [Cakmak, Huseyin Altug] Rize Kackar Govt Hosp, Dept Cardiol, Rize, Turkey; [Gunbatar, Hulya] Yuzuncu Yil Univ, Fac Med, Dept Pulm Dis, TR-65100 Van, Turkey; [Tosu, Aydin Rodi] Mehmet Akif Ersoy Thorac & Cardiovasc Surg Educ &, Dept Cardiol, Istanbul, Turkey; [Yaman, Mehmet] Samsun Educ & Training Hosp, Dept Cardiol, Samsun, Turkey en_US
dc.description Gumrukcuoglu, Hasan Ali/0000-0002-5972-9870 en_US
dc.description.abstract Background and Objectives: Obstructive sleep apnea syndrome (OSAS) is associated with increased arterial stiffness and cardiovascular complications. The objective of this study was to assess whether the color M-mode-derived propagation velocity of the descending thoracic aorta (aortic velocity propagation, AVP) was an echocardiographic marker for arterial stiffness in OSAS. Subjects and Methods: : The study population included 116 patients with OSAS and 90 age and gender-matched control subjects. The patients with OSAS were categorized according to their apnea hypopnea index (AHI) as follows: mild to moderate degree (AHI 5-30) and severe degree (AHI >= 30). Aortofemoral pulse wave velocity (PWV), carotid intima-media thickness (CIMT), brachial artery flow-mediated dilatation (FMD), and AVP were measured to assess arterial stiffness. Results: AVP and FMD were significantly decreased in patients with OSAS compared to controls (p<0.001). PWV and CIMT were increased in the OSAS group compared to controls (p<0.001). Moreover, AVP and FMD were significantly decreased in the severe OSAS group compared to the mild to moderate OSAS group (p<0.001). PWV and CIMT were significantly increased in the severe group compared to the mild to moderate group (p<0.001). AVP was significantly positively correlated with FMD (r=0.564, p<0.001). However, it was found to be significantly inversely related to PWV (r=-0.580, p<0.001) and CIMT (r=-0.251, p<0.001). Conclusion: The measurement of AVP is a novel and practical echocardiographic method, which may be used to identify arterial stiffness in OSAS. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.4070/kcj.2015.45.6.500
dc.identifier.endpage 509 en_US
dc.identifier.issn 1738-5520
dc.identifier.issn 1738-5555
dc.identifier.issue 6 en_US
dc.identifier.pmid 26617653
dc.identifier.scopus 2-s2.0-84958605144
dc.identifier.scopusquality Q2
dc.identifier.startpage 500 en_US
dc.identifier.uri https://doi.org/10.4070/kcj.2015.45.6.500
dc.identifier.uri https://hdl.handle.net/20.500.14720/15042
dc.identifier.volume 45 en_US
dc.identifier.wos WOS:000365465800010
dc.identifier.wosquality Q3
dc.language.iso en en_US
dc.publisher Korean Soc Cardiology en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Aortic Velocity/Propagation en_US
dc.subject Obstructive Sleep Apnea en_US
dc.subject Vascular Stiffness en_US
dc.subject Pulse Wave Analysis en_US
dc.subject Echocardiography en_US
dc.title A Novel Echocardiographic Method for Assessing Arterial Stiffness in Obstructive Sleep Apnea Syndrome en_US
dc.type Article en_US

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