Cytogenetic and Oxidative Status of Cultured Lymphocytes After Exposure To Extracts From Rhizopogon Mushrooms (Agaricomycetes) in Vitro
dc.authorscopusid | 55098881900 | |
dc.authorscopusid | 57222724488 | |
dc.authorscopusid | 7102936166 | |
dc.authorscopusid | 7102214656 | |
dc.authorscopusid | 57211230574 | |
dc.authorwosid | Emsen, Bugrahan/T-2000-2017 | |
dc.authorwosid | Kaya, Abdullah/G-3028-2010 | |
dc.contributor.author | Emsen, B. | |
dc.contributor.author | Turel, A. | |
dc.contributor.author | Kaya, A. | |
dc.contributor.author | Aslan, A. | |
dc.contributor.author | Engin, T. | |
dc.date.accessioned | 2025-05-10T17:03:11Z | |
dc.date.available | 2025-05-10T17:03:11Z | |
dc.date.issued | 2021 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | Emsen B., Department of Biology, Kamil Özdağ Faculty of Science, Karamanoğlu Mehmetbey University, Karaman, Turkey; Turel A., Department of Biology, Kamil Özdağ Faculty of Science, Karamanoğlu Mehmetbey University, Karaman, Turkey; Kaya A., Department of Biology, Faculty of Science, Gazi University, Ankara, Turkey; Aslan A., Department of Pharmacology, Faculty of Pharmacy, Van Yüzüncü Yıl University, Van, Turkey, Department of Biology, Faculty of Arts and Science, Kyrgyz-Turkish Manas University, Bishkek, Kyrgyzstan; Engin T., Department of Physiology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey | en_US |
dc.description.abstract | In this study, acetone and water extracts obtained from edible mushrooms, Rhizopogon luteolus Fr. and Rh. roseolus (Corda) Th. Fr., containing important bioactive components were used. Total antioxidant capacity (TAC) and total oxidative stress (TOS) levels were examined on human peripheral lymphocyte culture treated with the respective extracts. Levels of genetic damage and cytotoxic effects of the respective extracts on lymphocytes were also tested. In general, when TAC levels of the extracts on cells were examined, a concentration-dependent increase was observed; a negative correlation was found between TOS data and concentration. Genotoxicity tests (chromosome aberration and micronucleus analysis) revealed that the concentrations of the extract applications did not significantly (P > 0.05) change genotoxicity on human peripheral lymphocyte culture compared to the negative control. Considering all of the results obtained, it was determined that applications of Rh. luteolus and Rh. roseolus extracts, especially at concentrations of 50 and 100 mg/L, increased the TAC value of lymphocytes, which play an important role in the human immune system, without causing genetic or oxidative stress. © 2021 by Begell House, Inc. www.begellhouse.com. | en_US |
dc.description.sponsorship | Karamano?lu Mehmetbey University Scientific Research Projects Commission; Karamanoğlu Mehmetbey University Scientific Research Projects Commission, (06-YL-19) | en_US |
dc.description.woscitationindex | Science Citation Index Expanded | |
dc.identifier.doi | 10.1615/IntJMedMushrooms.2021037653 | |
dc.identifier.endpage | 77 | en_US |
dc.identifier.issn | 1521-9437 | |
dc.identifier.issue | 3 | en_US |
dc.identifier.pmid | 33822500 | |
dc.identifier.scopus | 2-s2.0-85103824297 | |
dc.identifier.scopusquality | Q3 | |
dc.identifier.startpage | 67 | en_US |
dc.identifier.uri | https://doi.org/10.1615/IntJMedMushrooms.2021037653 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/5631 | |
dc.identifier.volume | 23 | en_US |
dc.identifier.wos | WOS:000637192500001 | |
dc.identifier.wosquality | Q4 | |
dc.language.iso | en | en_US |
dc.publisher | Begell House Inc. | en_US |
dc.relation.ispartof | International Journal of Medicinal Mushrooms | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Antioxidant | en_US |
dc.subject | Cytotoxicity | en_US |
dc.subject | Fungus | en_US |
dc.subject | Genotoxicity | en_US |
dc.subject | Medicinal Mushrooms | en_US |
dc.subject | Oxidative Stress | en_US |
dc.subject | Rhizopogon Mushrooms | en_US |
dc.title | Cytogenetic and Oxidative Status of Cultured Lymphocytes After Exposure To Extracts From Rhizopogon Mushrooms (Agaricomycetes) in Vitro | en_US |
dc.type | Article | en_US |