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Epidemiology of Pemphigus in Turkey: One-Year Prospective Study of 220 Cases

dc.authorid Gurel, Mehmet Salih/0000-0002-7031-6516
dc.authorid Uzun, Soner/0000-0001-7059-5474
dc.authorid Bilgic, Asli/0000-0001-7910-7908
dc.authorid Aytekin, Sema/0000-0003-1376-1573
dc.authorid Kartal, Demet/0000-0002-5502-7716
dc.authorid Erdem, Cengizhan/0000-0002-9312-5683
dc.authorid Durdu, Murat/0000-0003-1247-3932
dc.authorscopusid 6506898502
dc.authorscopusid 7006379059
dc.authorscopusid 6602518817
dc.authorscopusid 36437186900
dc.authorscopusid 57196150592
dc.authorscopusid 8912460400
dc.authorscopusid 56652100000
dc.authorwosid Kaya, Tamer/A-7664-2016
dc.authorwosid Odyakmaz Demirsoy, Evren/Aab-7136-2020
dc.authorwosid Durdu, Murat/H-9068-2019
dc.authorwosid Aktan, Sebnem/Aas-9706-2020
dc.authorwosid Erdem, Cengizhan/Aap-9013-2020
dc.authorwosid Savk, Ekin/Aac-4126-2021
dc.authorwosid Onsun, Nahide/G-2701-2011
dc.contributor.author Yayli, Savas
dc.contributor.author Harman, Mehmet
dc.contributor.author Baskan, Emel Bulbul
dc.contributor.author Karakas, Ayse Akman
dc.contributor.author Genc, Yeser
dc.contributor.author Turk, Bengu Gerceker
dc.contributor.author Uzun, Soner
dc.date.accessioned 2025-05-10T17:49:15Z
dc.date.available 2025-05-10T17:49:15Z
dc.date.issued 2017
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Yayli, Savas; Altun, Ece] Karadeniz Tech Univ, Dept Dermatol, Trabzon, Turkey; [Harman, Mehmet] Dicle Univ, Dept Dermatol, Diyarbakir, Turkey; [Baskan, Emel Bulbul] Uludag Univ, Dept Dermatol, Bursa, Turkey; [Karakas, Ayse Akman; Temel, Asli Bilgic; Uzun, Soner] Akdeniz Univ, Antalya, Turkey; [Genc, Yeser; Erdem, Cengizhan] Ankara Univ, Ankara, Turkey; [Turk, Bengu Gerceker] Ege Univ, Izmir, Turkey; [Demirsoy, Evren Odyakmaz] Kocaeli Univ, Izmit, Turkey; [Gunasti, Suhan; Gungor, Dilek] Cukurova Univ, Adana, Turkey; [Bilgili, Serap Gunes] Yuzuncu Yil Univ, Van, Turkey; [Ilter, Nilsel] Gazi Univ, Ankara, Turkey; [Ferahbas, Ayten; Kartal, Demet] Erciyes Univ, Kayseri, Turkey; [Savk, Ekin] Adnan Menderes Univ, Aydin, Turkey; [Afsar, Fatma Sule] Ataturk Training & Res Hosp, Izmir, Turkey; [Aytekin, Sema] Haydarpasa Numune Training & Res Hosp, Istanbul, Turkey; [Kaya, Tamer Irfan] Mersin Univ, Mersin, Turkey; [Hayta, Sibel Berksoy; Akyol, Melih] Cumhuriyet Univ, Mersin, Turkey; [Ozgen, Zuleyha] Marmara Univ, Istanbul, Turkey; [Gurel, Mehmet Salih; Aksu, Esra Koku] Istanbul Res & Training Hosp, Istanbul, Turkey; [Caliskan, Ercan] Gulhane Mil Med Acad, Ankara, Turkey; [Balci, Didem Didar] Tepecik Res & Training Hosp, Izmir, Turkey; [Gungor, Sule] Okmeydani Res & Training Hosp, Istanbul, Turkey; [Kapicioglu, Yelda] Inonu Univ, Malatya, Turkey; [Ozuguz, Pinar] Afyon Kocatepe Univ, Afyon, Turkey; [Aktan, Sebnem] Dokuz Eylul Univ, Izmir, Turkey; [Dogramaci, Asena] Mustafa Kemal Univ, Antakya, Turkey; [Kokcam, Ibrahim] Firat Univ, Elazig, Turkey; [Onsun, Nahide] Bezmialem Univ, Istanbul, Turkey; [Seckin, Deniz] Baskent Univ, Ankara, Turkey; [Durdu, Murat] Baskent Univ, Adana Hosp, Adana, Turkey; [Dursun, Recep] Baskent Univ, Konya Hosp, Konya, Turkey; [Daye, Munise] Necmettin Erbakan Univ, Konya, Turkey; [Dilek, Nursel] Recep Tayyip Erdogan Univ, Rize, Turkey; [Karabacak, Ercan] GATA Haydarpasa Hosp, Istanbul, Turkey en_US
dc.description Gurel, Mehmet Salih/0000-0002-7031-6516; Uzun, Soner/0000-0001-7059-5474; Bilgic, Asli/0000-0001-7910-7908; Aytekin, Sema/0000-0003-1376-1573; Kartal, Demet/0000-0002-5502-7716; Erdem, Cengizhan/0000-0002-9312-5683; Caliskan, Ercan/0000-0001-7311-2087; Onsun, Nahide/0000-0001-6259-0219; Aktan, Sebnem/0000-0002-0201-4663; Durdu, Murat/0000-0003-1247-3932 en_US
dc.description.abstract Pemphigus is a group of rare and life-threatening autoimmune blistering diseases of the skin and mucous membranes. Although they occur worldwide, their incidence shows wide geographical variation, and prospective data on the epidemiology of pemphigus are very limited. Objective of this work is to evaluate the incidence and epidemiological and clinical features of patients with pemphigus in Turkey. All patients newly diagnosed with pemphigus between June 2013 and June 2014 were prospectively enrolled in 33 dermatology departments in 20 different provinces from all seven regions of Turkey. Disease parameters including demography and clinical findings were recorded. A total of 220 patients were diagnosed with pemphigus during the 1-year period, with an annual incidence of 4.7 per million people in Turkey. Patients were predominantly women, with a male to female ratio of 1:1.41. The mean age at onset was 48.9 years. Pemphigus vulgaris (PV) was the commonest clinical subtype (n= 192; 87.3%), followed by pemphigus foliaceus (n= 21; 9.6%). The most common clinical subtype of PV was the mucocutaneous type (n= 83; 43.2%). The mean Pemphigus Disease Area Index was 28.14 +/- 22.21 (mean +/- Standard Deviation). The incidence rate of pemphigus in Turkey is similar to the countries of South-East Europe, higher than those reported for the Central and Northern European countries and lower than the countries around the Mediterranean Sea and Iran. Pemphigus is more frequent in middle-aged people and is more common in women. The most frequent subtype was PV, with a 9-fold higher incidence than pemphigus foliaceus. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.endpage 188 en_US
dc.identifier.issn 1330-027X
dc.identifier.issn 1847-6538
dc.identifier.issue 3 en_US
dc.identifier.pmid 29252169
dc.identifier.scopus 2-s2.0-85032013337
dc.identifier.scopusquality Q4
dc.identifier.startpage 181 en_US
dc.identifier.uri https://hdl.handle.net/20.500.14720/17402
dc.identifier.volume 25 en_US
dc.identifier.wos WOS:000413524200001
dc.identifier.wosquality Q4
dc.language.iso en en_US
dc.publisher Croation dermatovenerological Soc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Pemphigus en_US
dc.subject Epidemiology en_US
dc.title Epidemiology of Pemphigus in Turkey: One-Year Prospective Study of 220 Cases en_US
dc.type Article en_US

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