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The Levels of Trace Elements and Heavy Metals in Patients With Acute Migraine Headache

dc.authorscopusid 36096565100
dc.authorscopusid 55554281100
dc.authorscopusid 42861696800
dc.authorscopusid 57158783300
dc.authorscopusid 8866326000
dc.authorscopusid 14059430200
dc.authorscopusid 6504132869
dc.authorwosid Kalemci, Orhan/P-6893-2019
dc.authorwosid Gönüllü, Edip/Aav-7377-2021
dc.authorwosid Gonullu, Hayriye/Aau-9606-2021
dc.authorwosid Aycan, Abdurrahman/Jdw-3925-2023
dc.contributor.author Gonullu, Hayriye
dc.contributor.author Gonullu, Edip
dc.contributor.author Karadas, Sevdegul
dc.contributor.author Arslan, Mehmet
dc.contributor.author Kalemci, Orhan
dc.contributor.author Aycan, Abdurrahman
dc.contributor.author Demir, Halit
dc.date.accessioned 2025-05-10T16:58:31Z
dc.date.available 2025-05-10T16:58:31Z
dc.date.issued 2015
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Gonullu, Hayriye; Karadas, Sevdegul] Yuzuncu Yil Univ, Sch Med, Dept Emergency Med, Van, Turkey; [Arslan, Mehmet] Yuzuncu Yil Univ, Sch Med, Dept Neurosurg, Van, Turkey; [Sayin, Refah] Yuzuncu Yil Univ, Sch Med, Dept Neurol, Van, Turkey; [Demir, Halit] Yuzuncu Yil Univ, Sch Med, Dept Chem, Van, Turkey; [Gonullu, Edip] Van Reg Training & Res Hosp, Anesteshiol, Van, Turkey; [Aycan, Abdurrahman] Van Reg Training & Res Hosp, Neurosurg, Van, Turkey; [Kalemci, Orhan] Dokuz Eylul Univ, Sch Med, Dept Neurosurg, Izmir, Turkey en_US
dc.description.abstract Objective: To compare the levels of trace elements and heavy metal in patients with acute migraine and healthy controls. Methods: The prospective study was conducted at Yuzuncu Yil University, Turkey, from May to July 2013, and comprised migraine patients and an equal number of healthy controls. International Headache Society classification was used for diagnosing migraine. Serum copper, zinc, lead, iron, cadmium, cobalt, manganese, and magnesium levels were measured in both groups. Metal concentrations were assessed by atomic absorption spectrophotometry. SPSS 13 was used for statistical analysis. Results: There were 25 migraine patients with an average age of 36.4+/-8.9 years and 25 healthy controls with a mean age of 42.4+/-9.5 years. Cadmium, iron, manganese and lead levels were significantly elevated in the patients compared to the controls (p<0.05 each), while copper, magnesium and zinc were decreased and cobalt demonstrated no change. Conclusions: Trace elements and heavy metals may have a role in the genesis of considerable oxidative stress in patients with acute migraine headache. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.endpage 697 en_US
dc.identifier.issn 0030-9982
dc.identifier.issue 7 en_US
dc.identifier.pmid 26160074
dc.identifier.scopus 2-s2.0-84934779995
dc.identifier.scopusquality Q3
dc.identifier.startpage 694 en_US
dc.identifier.uri https://hdl.handle.net/20.500.14720/4299
dc.identifier.volume 65 en_US
dc.identifier.wos WOS:000360442600002
dc.identifier.wosquality Q4
dc.language.iso en en_US
dc.publisher Pakistan Medical Assoc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Acute Migraine Attack en_US
dc.subject Trace Elements en_US
dc.subject Heavy Metals en_US
dc.title The Levels of Trace Elements and Heavy Metals in Patients With Acute Migraine Headache en_US
dc.type Article en_US

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