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Associations Between the Standardized Uptake Value of 18f-Fdg Pet/Ct and Demographic, Clinical, Pathological, Radiological Factors in Lung Cancer

dc.authorid Ekin, Selami/0000-0001-5922-0348
dc.authorid Arisoy, Ahmet/0000-0003-2442-6498
dc.authorid Demir, Yusuf/0000-0001-6762-1977
dc.authorscopusid 54390006700
dc.authorscopusid 56416203300
dc.authorscopusid 35745637500
dc.authorscopusid 35094022200
dc.authorscopusid 26030385100
dc.authorwosid Ekin, Selami/Aak-1935-2021
dc.authorwosid Arisoy, Ahmet/A-3336-2014
dc.authorwosid Demir, Yusuf/L-2096-2013
dc.contributor.author Sunnetcioglu, Aysel
dc.contributor.author Arisoy, Ahmet
dc.contributor.author Demir, Yusuf
dc.contributor.author Ekin, Selami
dc.contributor.author Dogan, Erkan
dc.date.accessioned 2025-05-10T16:56:58Z
dc.date.available 2025-05-10T16:56:58Z
dc.date.issued 2015
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Sunnetcioglu, Aysel; Arisoy, Ahmet] Yuzuncu Yil Univ, Sch Med, Dept Chest Dis, TR-65100 Van, Turkey; [Demir, Yusuf; Ekin, Selami] Yuzuncu Yil Univ, Sch Med, Dept Nucl Med, TR-65100 Van, Turkey; [Dogan, Erkan] Yuzuncu Yil Univ, Sch Med, Dept Med Oncol, TR-65100 Van, Turkey en_US
dc.description Ekin, Selami/0000-0001-5922-0348; Arisoy, Ahmet/0000-0003-2442-6498; Demir, Yusuf/0000-0001-6762-1977 en_US
dc.description.abstract Objectives: F-18-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is extensively used to diagnose and stage of lung cancer. The aim of the current study was to investigate the correlation of demographic, clinical, pathological and radiological factors with primer tumor FDG Uptake in patients with lung cancer. Materials and methods: This cross-sectional, clinical study was performed on a total of 57 lung cancer patients newly diagnosed that underwent FDG PET/CT. In addition to descriptive variables, histopathological diagnosis, tumor site and size, hemoglobin level, red cell distribution width, neutrophil to lymphocyte ratio were noted for each patient. The correlation of these variables to SUVmax values in FDG PET/CT was investigated. Results: A total of 57 patients (4 women, 53 men) with an average age of 60.8 +/- 9.4 (range: 33-89) participated in the study. Histopathological diagnoses were consistent with squamous cell carcinoma (28, 49.1%), adenocarcinoma (15, 26.3%) and small cell cancer (14, 24.6%). The SUVmax of primary tumor was positively correlated with tumor size (P<0.001). The tumor SUVmax of squamous cell carcinoma (SqCC) (17.49 +/- 8.37) was higher than that of adenocarcinoma (AC) (12.80 +/- 4.77) and small cell carcinoma (SCC) (12.40 +/- 5.80) (P=0.038). Conclusion: SUVmax value was significantly higher for squamous cell carcinoma and it SUVmax values in PET scans was found to be positively correlated with tumor size. This study suggests that, tumor size and histologic subtype had influences upon FDG uptake in lung cancer. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.endpage 15800 en_US
dc.identifier.issn 1940-5901
dc.identifier.issue 9 en_US
dc.identifier.pmid 26629078
dc.identifier.scopus 2-s2.0-84946605671
dc.identifier.scopusquality N/A
dc.identifier.startpage 15794 en_US
dc.identifier.uri https://hdl.handle.net/20.500.14720/3888
dc.identifier.volume 8 en_US
dc.identifier.wos WOS:000367911200091
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher E-century Publishing Corp en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Lung Cancer en_US
dc.subject Fdg en_US
dc.subject Pet/Ct en_US
dc.subject Suv en_US
dc.subject Neutrophil-Lymphocyte Ratio en_US
dc.title Associations Between the Standardized Uptake Value of 18f-Fdg Pet/Ct and Demographic, Clinical, Pathological, Radiological Factors in Lung Cancer en_US
dc.type Article en_US

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