Intermolecular Heterocyclization of Alkynones With 2-Mercaptoacetaldehyde Under Metal-Free Conditions: Synthesis of 2,3-Disubstituted Thiophenes
| dc.authorid | Menges, Nurettin/0000-0002-5990-6275 | |
| dc.authorscopusid | 57192419562 | |
| dc.authorscopusid | 57209033775 | |
| dc.authorscopusid | 36872923100 | |
| dc.authorscopusid | 26664743800 | |
| dc.authorscopusid | 23973608700 | |
| dc.authorscopusid | 7006382595 | |
| dc.authorwosid | Koza, Gani/Aai-3325-2021 | |
| dc.authorwosid | Vatansever, Erol/P-2418-2019 | |
| dc.authorwosid | Menges, Nurettin/F-9678-2016 | |
| dc.contributor.author | Vatansever, Erol Can | |
| dc.contributor.author | Kilic, Kubra | |
| dc.contributor.author | Ozer, Merve Sinem | |
| dc.contributor.author | Koza, Gani | |
| dc.contributor.author | Menges, Nurettin | |
| dc.contributor.author | Balci, Metin | |
| dc.date.accessioned | 2025-05-10T17:11:17Z | |
| dc.date.available | 2025-05-10T17:11:17Z | |
| dc.date.issued | 2015 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Vatansever, Erol Can; Kilic, Kubra; Ozer, Merve Sinem; Menges, Nurettin; Balci, Metin] Middle E Tech Univ, Dept Chem, TR-06800 Ankara, Turkey; [Kilic, Kubra; Koza, Gani] Ahi Evran Univ, Dept Chem, Kirsehir, Turkey; [Menges, Nurettin] Yuzuncu Yil Univ, Fac Pharm, TR-65100 Van, Turkey | en_US |
| dc.description | Menges, Nurettin/0000-0002-5990-6275 | en_US |
| dc.description.abstract | A concise and regioselective approach for the synthesis of 2,3-disubstituted thiophene derivatives has been developed. The synthetic strategy relies on the reaction of an in situ generated 2-mercaptoacetaldehyde with various alkynones. Furthermore, we calculated the energy gap between the HOMO and the LUMO orbitals of all compounds and observed that the introduction of a strong electron-withdrawing group decreased the HOMO-LUMO energy gap. (C) 2015 Elsevier Ltd. All rights reserved. | en_US |
| dc.description.sponsorship | Scientific and Technological Research Council of Turkey (TUBITAK) [TBAG-112 T360]; Turkish Academy of Sciences (TUBA); Yuzuncu Yil University [YYU-BAP-2014-ECZ-B170]; Middle East Technical University (METU) | en_US |
| dc.description.sponsorship | Financial support from the Scientific and Technological Research Council of Turkey (TUBITAK, Grant No. TBAG-112 T360), the Turkish Academy of Sciences (TUBA), Middle East Technical University (METU), and Yuzuncu Yil University (Grant No. YYU-BAP-2014-ECZ-B170) are gratefully acknowledged. | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded - Index Chemicus | |
| dc.identifier.doi | 10.1016/j.tetlet.2015.07.090 | |
| dc.identifier.endpage | 5389 | en_US |
| dc.identifier.issn | 0040-4039 | |
| dc.identifier.issn | 1873-3581 | |
| dc.identifier.issue | 40 | en_US |
| dc.identifier.scopus | 2-s2.0-84940721375 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 5386 | en_US |
| dc.identifier.uri | https://doi.org/10.1016/j.tetlet.2015.07.090 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/7697 | |
| dc.identifier.volume | 56 | en_US |
| dc.identifier.wos | WOS:000362533900004 | |
| dc.identifier.wosquality | Q3 | |
| dc.language.iso | en | en_US |
| dc.publisher | Pergamon-elsevier Science Ltd | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Alkynes | en_US |
| dc.subject | Cyclization | en_US |
| dc.subject | Alkynones | en_US |
| dc.subject | 2-Mercaptoacetaldehyde | en_US |
| dc.subject | 2,3-Disubstituted Thiophenes | en_US |
| dc.title | Intermolecular Heterocyclization of Alkynones With 2-Mercaptoacetaldehyde Under Metal-Free Conditions: Synthesis of 2,3-Disubstituted Thiophenes | en_US |
| dc.type | Article | en_US |