Insulin Resistance Is Increased in Patients With Vitiligo
dc.authorscopusid | 26425048800 | |
dc.authorscopusid | 55903409200 | |
dc.authorscopusid | 9280148200 | |
dc.authorwosid | Karadag, Ayse/V-7974-2018 | |
dc.contributor.author | Karadag, Ayse Serap | |
dc.contributor.author | Tutal, Emre | |
dc.contributor.author | Ertugrul, Derun Taner | |
dc.date.accessioned | 2025-05-10T17:26:23Z | |
dc.date.available | 2025-05-10T17:26:23Z | |
dc.date.issued | 2011 | |
dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
dc.department-temp | [Karadag, Ayse Serap] Yuzuncu Yil Univ, Fac Med, Dept Dermatol, TR-65300 Van, Turkey; [Tutal, Emre] Ankara Baskent Univ Hosp, Dept Internal Med, Fac Med, Ankara, Turkey; [Ertugrul, Derun Taner] Ankara Kecioren Res & Training Hosp, Div Endocrinol & Metab, Dept Internal Med, Ankara, Turkey | en_US |
dc.description.abstract | The aim of this study was to evaluate the relationship between vitiligo and insulin resistance (IR). A total of 96 subjects were included in the study; 57 patients with vitiligo and 39 subjects in an age and a body mass index-matched control group. In fasting blood samples, insulin, C-peptide, glucose, total cholesterol, triglyceride, low-density lipoprotein-cholesterol (LDL-C) and high-density lipoprotein-cholesterol (HDL-C) were measured. IR was calculated with the homeostasis model assessment-IR (HOMA-IR) method. Comparison of the vitiligo and the control groups revealed that patients with vitiligo had higher IR (2.3 vs. 2.0,p<0.01), higher insulin and C-peptide levels (p<0.001, p<0.001, respectively), higher LDL/HDL ratio and lower HDL-C levels (p<0.01, p<0.0001, respectively). Systolic blood pressures of patients with vitiligo were also higher compared with control subjects (p<0.01). Further experimental and clinical studies are needed to elucidate the molecular mechanisms underlying this association. | en_US |
dc.description.woscitationindex | Science Citation Index Expanded | |
dc.identifier.doi | 10.2340/00015555-1141 | |
dc.identifier.endpage | 544 | en_US |
dc.identifier.issn | 0001-5555 | |
dc.identifier.issn | 1651-2057 | |
dc.identifier.issue | 5 | en_US |
dc.identifier.pmid | 21597678 | |
dc.identifier.scopus | 2-s2.0-80052067435 | |
dc.identifier.scopusquality | Q1 | |
dc.identifier.startpage | 541 | en_US |
dc.identifier.uri | https://doi.org/10.2340/00015555-1141 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14720/11661 | |
dc.identifier.volume | 91 | en_US |
dc.identifier.wos | WOS:000294887800009 | |
dc.identifier.wosquality | Q1 | |
dc.language.iso | en | en_US |
dc.publisher | Acta dermato-venereologica | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Homa-Ir | en_US |
dc.subject | Insulin Resistance | en_US |
dc.subject | Vitiligo | en_US |
dc.title | Insulin Resistance Is Increased in Patients With Vitiligo | en_US |
dc.type | Article | en_US |