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Analyzing the Effects of Platelet Gel on Knee Osteoarthritis in the Rat Model

dc.authorscopusid 37101533000
dc.authorscopusid 55893403600
dc.authorwosid Guner, Savas/Aah-4113-2020
dc.authorwosid Büyükbebeci, Orhan/Aah-1356-2020
dc.contributor.author Guner, Savas
dc.contributor.author Buyukbebeci, Orhan
dc.date.accessioned 2025-05-10T17:44:49Z
dc.date.available 2025-05-10T17:44:49Z
dc.date.issued 2013
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Guner, Savas] Yuzuncu Yil Univ, Dept Trauma & Orthoped Surg, Sch Med, Van, Turkey; [Buyukbebeci, Orhan] Gaziantep Univ, Dept Trauma & Orthoped Surg, Sch Med, Gaziantep, Turkey en_US
dc.description.abstract Platelet gel (PG) includes concentrated dose of growth factors which plays role in physiological processes of healing. The goal of this study is to evaluate repairing effects of intra-articular injection of PG use in a rat model of knee osteoarthritis (OA). A total of 20 rats were randomly distributed into a PG group and a control group. Both the groups were induced OA in knee joints with intra-articular formaline injection. The rats in the PG group and the control group were injected in the knee joint with PG and 0.9% NaCl solution, respectively. Two weeks after last injections, all rats were sacrificed by ether asphyxiation. Tissue samples were obtained from the knee joints and were examined histopathologically. No statistically significant differences were found between the groups regarding cartilage healing (P > .05). We were unable to determine any beneficial or harmful effects of PG on joint cartilage healing in OA. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1177/1076029612452117
dc.identifier.endpage 498 en_US
dc.identifier.issn 1076-0296
dc.identifier.issn 1938-2723
dc.identifier.issue 5 en_US
dc.identifier.pmid 22790657
dc.identifier.scopus 2-s2.0-84884221179
dc.identifier.scopusquality Q2
dc.identifier.startpage 494 en_US
dc.identifier.uri https://doi.org/10.1177/1076029612452117
dc.identifier.uri https://hdl.handle.net/20.500.14720/16176
dc.identifier.volume 19 en_US
dc.identifier.wos WOS:000324472400005
dc.identifier.wosquality Q2
dc.language.iso en en_US
dc.publisher Sage Publications inc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Platelet Gel en_US
dc.subject Osteoarthritis en_US
dc.subject Treatment en_US
dc.title Analyzing the Effects of Platelet Gel on Knee Osteoarthritis in the Rat Model en_US
dc.type Article en_US

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