Assesment of Hematotoxic, Oxidative and Genotoxic Damage Potentials of Fipronil in Rainbow Trout Oncorhynchus Mykiss, Walbaum
| dc.authorid | Cilingir Yeltekin, Asli/0000-0003-0071-7434 | |
| dc.authorid | Caglar, Ozge/0000-0003-1412-8411 | |
| dc.authorscopusid | 36524329100 | |
| dc.authorscopusid | 55636597200 | |
| dc.authorscopusid | 56189749500 | |
| dc.authorscopusid | 54385688800 | |
| dc.authorscopusid | 57520408900 | |
| dc.authorscopusid | 9134233800 | |
| dc.authorscopusid | 23395887300 | |
| dc.authorwosid | Uçar, Arzu/Aaa-2325-2022 | |
| dc.authorwosid | , Aslı/Afm-3417-2022 | |
| dc.authorwosid | Parlak, Veysel/L-3436-2018 | |
| dc.authorwosid | Alak, Gonca/Hzk-0144-2023 | |
| dc.authorwosid | Türkez, Hasan/Aaq-4905-2020 | |
| dc.authorwosid | Çağlar Yıldırım, Özge/Aay-9490-2021 | |
| dc.authorwosid | Atamanalp, Muhammed/Aag-2950-2020 | |
| dc.contributor.author | Ucar, Arzu | |
| dc.contributor.author | Parlak, Veysel | |
| dc.contributor.author | Cilingir Yeltekin, Asli | |
| dc.contributor.author | Ozgeris, Fatma Betul | |
| dc.contributor.author | Caglar, Ozge | |
| dc.contributor.author | Turkez, Hasan | |
| dc.contributor.author | Atamanalp, Muhammed | |
| dc.date.accessioned | 2025-05-10T17:07:47Z | |
| dc.date.available | 2025-05-10T17:07:47Z | |
| dc.date.issued | 2021 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Ucar, Arzu; Alak, Gonca; Atamanalp, Muhammed] Ataturk Univ, Fac Fisheries, Dept Aquaculture, Erzurum, Turkey; [Parlak, Veysel] Ataturk Univ, Fac Fisheries, Dept Basic Sci, Erzurum, Turkey; [Cilingir Yeltekin, Asli] Yuzuncu Yil Univ, Fac Sci, Dept Chem, Van, Turkey; [Ozgeris, Fatma Betul] Ataturk Univ, Fac Hlth Sci, Dept Nutr & Dietet, Erzurum, Turkey; [Caglar, Ozge] Erzurum Tech Univ, Dept Mol Biol & Genet, Fac Sci, Erzurum, Turkey; [Turkez, Hasan] Erzurum Tech Univ, Fac Med, Dept Med Biol, Erzurum, Turkey | en_US |
| dc.description | Cilingir Yeltekin, Asli/0000-0003-0071-7434; Caglar, Ozge/0000-0003-1412-8411 | en_US |
| dc.description.abstract | In this study, changes in the blood tissue of rainbow trout (Oncorhynchus mykiss, Walbaum, 1792) caused by Fipronil (FP) insecticide were investigated using different biomarkers (Hematology parameters, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), malondialdehyde (MDA), paraoxonase (PON), arylesterase (ARE), myeleperoxidase (MPO), micronucleus (MN), 8-hydroxy-2-deoxyguanosine (8-OHdG)) level and caspase-3 activity. Statistically significant alterations in hematology parameters occurred with FP effect. In blood tissue, dose-dependent inhibition was determined in SOD-CAT-GPX-PON and ARE enzyme activities, but MDA and MPO were induced statistically significant. The results of MN assay were compared with the control group and it was obtained that genotoxicity of different dose groups was similar. The level of 8-OHdG and the activity and caspase-3 examined in blood tissue was increased depending on the dose. It was determined with different biomarkers that this insecticide caused physiological stress changes in the tissues examined. | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.doi | 10.1080/15376516.2020.1831122 | |
| dc.identifier.endpage | 80 | en_US |
| dc.identifier.issn | 1537-6516 | |
| dc.identifier.issn | 1537-6524 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.pmid | 33050807 | |
| dc.identifier.scopus | 2-s2.0-85094133446 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.startpage | 73 | en_US |
| dc.identifier.uri | https://doi.org/10.1080/15376516.2020.1831122 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/6883 | |
| dc.identifier.volume | 31 | en_US |
| dc.identifier.wos | WOS:000583825800001 | |
| dc.identifier.wosquality | Q2 | |
| dc.language.iso | en | en_US |
| dc.publisher | Taylor & Francis Ltd | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Fipronil | en_US |
| dc.subject | O | en_US |
| dc.subject | Mykiss | en_US |
| dc.subject | Hematology | en_US |
| dc.subject | Enzyme Parameters | en_US |
| dc.subject | 8-Ohdg | en_US |
| dc.subject | Caspase-3 | en_US |
| dc.title | Assesment of Hematotoxic, Oxidative and Genotoxic Damage Potentials of Fipronil in Rainbow Trout Oncorhynchus Mykiss, Walbaum | en_US |
| dc.type | Article | en_US |