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Determination of Oxidative Stress Level and Some Antioxidant Activities in Refractory Epilepsy Patients

dc.authorid Demir, Canan/0000-0002-4204-9756
dc.authorscopusid 56368632300
dc.authorscopusid 57197170055
dc.authorwosid Demir, Canan/Gwm-8855-2022
dc.contributor.author Yilgor, Abdullah
dc.contributor.author Demir, Canan
dc.date.accessioned 2025-05-10T17:23:54Z
dc.date.available 2025-05-10T17:23:54Z
dc.date.issued 2024
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Yilgor, Abdullah] Van YuzuncuYil Univ, Fac Med, Dept Neurol, TR-65200 Van, Turkiye; [Demir, Canan] Vocat Sch Hlth Serv, Van, Turkiye en_US
dc.description Demir, Canan/0000-0002-4204-9756 en_US
dc.description.abstract The aim of this study was to determine the levels of superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) in patients with refractory epilepsy. Serum superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) levels were determined using the spectrophotometer method. Refractory epilepsy patients' serum superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) levels were statistically significant compared to the healthy control group (p < 0.05). In conclusion, superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) levels may play an important role in the etiopathogenesis of refractory epilepsy. This study was the first to investigate some parameters in refractory epilepsy disease. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1038/s41598-024-57224-6
dc.identifier.issn 2045-2322
dc.identifier.issue 1 en_US
dc.identifier.pmid 38509121
dc.identifier.scopus 2-s2.0-85188238402
dc.identifier.scopusquality Q1
dc.identifier.uri https://doi.org/10.1038/s41598-024-57224-6
dc.identifier.uri https://hdl.handle.net/20.500.14720/11022
dc.identifier.volume 14 en_US
dc.identifier.wos WOS:001192455600039
dc.identifier.wosquality Q2
dc.language.iso en en_US
dc.publisher Nature Portfolio en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Catalase en_US
dc.subject Malondialdehyde en_US
dc.subject Refractory Epilepsy en_US
dc.subject Superoxide Dismutase en_US
dc.title Determination of Oxidative Stress Level and Some Antioxidant Activities in Refractory Epilepsy Patients en_US
dc.type Article en_US

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