TR-Dizin İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14720/5

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3d Location Optimization of Multiple Unmanned Aerial Vehicle Base Stations in Next-Generation Cellular Networks and a New Meta-Heuristic Approach
(Gazi Univ, Fac Engineering Architecture, 2021) Ozdag, Recep
The use of Unmanned Aerial Vehicles (UAVs) as mobile Base Stations (BSs) in wireless communication is emerging as an effective technique that should be used for the services planned in the next-generation cellular networks or in disaster situations. Currently, effective 3D placement of BS mounted on UAVs or Drones (Drone-BS), also called Low-altitude Air Platforms, in the defined area significantly increases the Quality of Service (QoS) of wireless communication. This study has been aimed to be performed dynamic deployments (location optimization) of Drone-BSs randomly distributed in the 3D plane in order to optimally cover the users in the urban environment according to the Air-to-Ground (ATG) model. Using new approaches based on the Electromagnetism-Like (EML) Algorithm and the Whale Optimization Algorithm (WOA), which are widely used in the literature and are meta-heuristic, it was planned to be covered the maximum number of users on the ground by multiple Drone-BSs. In addition, Extensive-interval Optimal Fitness Search Algorithm (EOFSA-EML) and Discrete-interval Optimal Fitness Search Algorithm (DOFSA-EML) approaches were developed based on the EML algorithm. Based on comparison metrics for multiple Drone-BSs distributed by EOFSA-EML, DOFSA-EML, and Pure-WOA, it has been found that EML-based algorithms achieve optimal results compared to Pure-WOA.
Abo and Rh Blood Groups Frequency in Men and Women Living in Eastern Turkey
(2006) Dilek, I.; Demir, C.; Bay, A.; Akdeniz, H.; Öner, A.F.
Objective: ABO and Rh blood groups which are basic for determination of blood compatibility consist of the most important tests of blood center. In this study, we aimed to find out the rates of ABO and Rh blood groups in male and female donors in our region. Therefore, donors attending to our blood center within the last five years were investigated taken into account their gender. Methods: Blood groups were examined by gel-centrifugation or tube agglutination methods. Results: Out of totally 33.193 individuals, 14.716 were female (44.3%) and 18.477 males (55.7%), and average age was 34 (range 20-60 years old). Taken into account the whole donors, A blood type was found as 43.8%, O blood type 30.8%, B blood type 16.2% and AB blood type 8.6% in rate. With respect to blood type frequency in genders group A was in the rate of 44.1% and 43.6%, group O 31% and 30.5%, group B 16.3% and 16.1% and group AB 8.6% and 9.8% in women and men, respectively. The Rh positivity rate into totally whole donors was 85.5%, being 86.0% in men and 84.8% in women. Conclusion: ABO and Rh blood groups rates were very near to each other in women and men, and also the average rate was very similar to averages in Turkey.
The Activities of Gst Isozymes in Stomach Tissues of Female Obese Patients
(Walter de Gruyter Gmbh, 2020) Yilmaz, Can; Bulus, Hakan; Oguztuzun, Serpil; Cihan, Mehmethan; Fidan, Ceylan
Objectives: Obesity has become an important public health problem because of its increasing prevalence and relation with many diseases and mortality. Studies have shown its association with oxidative stress. In this study, the effect of obesity on total amount of thiol and some glutathione S-transferase (GST) isozymes were investigated which could serve as an important criteria in dose adjustment of some certain drugs in obese. Methods: The gastric tissues removed by gastrectomy operation from 29 morbid obese female patients were analysed for thiol levels and activities of total GST, GSTT1-1 and GSTM1-1. Patients were grouped according to age, presence of hypertension and/or diabetes, and family history. Results: The average total thiol was 131.22 (+/- 7.74) nmol/mg protein with no significant differences in between the groups. GSTT1 specific activities were about 20% higher in four groups: with ages over 35 years old, with hypertension, without diabetes and finally without family history, with respect to other groups. The differences between total GST and GSTM1 activity levels of experimental groups were not significant. Conclusions: This is the first study to compare activities of GST isozymes and total thiol content in the stomach tissues of obese female patients accompanying some common metabolic disorders, age and family history.
Albendazol Kullanımı Sonrası, Nadir Bir Komplikasyon: Kronik Granulamatöz İnflamasyon (Olgu Sunumu)
(2004) Işık, Ahmet Feridun; Bayram, İrfan; Er, Metin
Akciğer hidatik kistleri halen ülkemiz için önemli bir sorun olarak durmaktadır. Tedavisinde öncelik cerrahi yöntemler kullanılırken, son 15 yılda benzimadazol karbamat grubu ilaçlar denenmektedir. Ancak bu tedavi, akciğerlerin dışarıya açık organlar olması nedeniyle tam kür sağlamayabilmektedir. Canlılığını yitiren kistler komplikasyonlara açık hale gelmektedir. Bunlar tekrarlayan enfeksiyon, apse, bronşektazi, hemoptizi ve ağır pnömoni olarak sayılabilir. Patoloji raporunda eşlik eden kronik kazeifiye granulamatöz iltihap bildirilmesi üzerine, akciğer hidatik kistlerinin ilaçla tedavisinin yol açabileceği komplikasyonlan vurgulamak amacıyla olgumuzu paylaşmak istedik.
Analysis of Factors Effecting Pisa 2015 Mathematics Literacy Via Educational Data Mining
(Turkish Education Assoc, 2020) Gure, Ozlem Bezek; Kayri, Murat; Erdogan, Fevzi
The aim of this study is to determine the factors affecting PISA 2015 Mathematics literacy by using data mining methods such as Multilayer Perceptron Artificial Neural Networks and Random Forest. Cause and effect relation within the context of the study was tried to be discovered by means of data mining methods at the level of deep learning. In terms of Prediction Ability, the findings of the method whose performance was high were accepted as the factors determining the qualifications in Mathematics literacy in Turkey. In this study, the information, which was collected from a total of 4422 students, 215 (49%) of whom were boys and 2257 (51%) of whom were girls participating in PISA 2015 test, was used. The scores, which the students, having gone in for PISA 2015 test, got from mathematics test, and dependent variables and 25 variables, which were thought to have connection with dependent variables institutionally, were included in the analysis as predictors. As a result of analysis, it was witnessed that Random Forest (RF) method made prediction with smaller errors in terms of a number of performance indicators. The factors that random forest method found important after anxiety variable are Turkish success level of students, mother education level, motivation level, the belief in epistemology, interest level of teachers and class disciplinary environment, respectively. The statistical meaning, significance and impact levels of other variables were tackled together with their details in this study. It is expected that this study will set an example for data mining use in the process of educational studies and that the factors whose affects were found out about the students' mathematics literacy will shed light on National Education system.
Anterior Omuz İnstabilitelerinde Dikiş Kancaları ile Bankart Tamirinin Erken Sonuçları
(2000) Tuncay, Ibrahim; Akpinar, Fuat; Tosun, Nihat
Amaç: Biyomekanik olarak anteroinferior glenohumeral ligaman restorasyonunu sağlayan Bankart tamiri, anterior glenohumeral eklem kronik instabilitesi tedavisinde altın standart olarak kabul edilmektedir. Çalışmamızda, dikiş kancaları (suture anchors) yardımıyla Bankart tamiri uyguladığımız anterior omuz instabiliteli hastalarda erken sonuçlar değerlendirildi. Çalışma planı: 1998-1999 yıllarında anterior omuz instabilitesi tanısıyla açık Bankart tamiri girişimi uygulanan ve en az altı aylık takipleri tamamlanan 16 erkek hasta (ort. yaş 23; yaş dağılımı 20-27) incelendi. Ortalama ilk çıkık- cerrahi girişim süresi beş yıl ve ortalama çıkık sayısı dokuz idi. Ameliyat öncesi 11 hastada (%68) manyetik rezonans görüntüleme, beş hastada (%32) tanısal artroskopi uygulandı. On hastada (% 62) dikiş kancaları yardımıyla açık Bankart tamiri, altı hastada (%38) medial kapsüler kaydırmayla birlikte Bankart tamiri uygulandı. Sonuçlar Rowe’nin Bankart skalasına göre değerlendirildi. Sonuçlar: Ortalama takip süresi 11.5 aydı (dağılım 6-15 ay) . Bir hastada (%6) postoperatif ikinci ayda aşırı zorlama sonrası gelişen rekürens nedeniyle revizyon uygulandı. Diğer hastaların hiçbirinde herhangi bir komplikasyona rastlanmadı. Bankart skoru 11 olguda mükemmel, iki olguda iyi, iki olguda orta, bir olguda kötü olarak değerlendirildi. Nüks gözlenen olgu dışında, tüm olgularda 10 dereceyi aşan dış rotasyon kısıtlılığı saptanmadı.Çıkarımlar: Erken dönem gözlemlerimiz, dikiş kancaları yardımıyla gerçekleştirilen açık Bankart tamirinin düşük rekürens oranı ve minimal eklem hareket kısıtlılığı ile birlikte uygun bir tedavi yöntemi olduğunu göstermektedir.
Antioxidant and Anticholinesterase Constituents of Salvia Poculata
(Tubitak Scientific & Technological Research Council Turkey, 2009) Kolak, Ufuk; Hacibekiroglu, Isil; Ozturk, Mehmet; Ozgokce, Fevzi; Topcu, Guelacti; Ulubelen, Ayhan
Two triterpenoids, namely 2 alpha,3 alpha-dihydroxy-24-nor-4(23), 12-oleanadien-28-oic acid (1) and ursolic acid (2); 4. avonoids, namely 5-hydroxy-7,4'-dimethoxyflavone (3), cirsimaritin (4), eupatilin (5), and salvigenin (6); a diterpenoid, namely sclareol (7); and a steroid, namely beta-sitosterol (8), were isolated from the aerial parts of Salvia poculata Nab., a Turkish endemic Salvia species. Total phenolic and flavonoid contents of the crude extract were determined as pyrocatechol and quercetin equivalents, respectively. The antioxidant activity of the crude extract and the isolated compounds (2-8) was established using beta-carotene bleaching, superoxide anion radical, and ABTS cation radical scavenging activity. In addition, the anticholinesterase activity of the crude extract and the isolated compounds (2-8) against the enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) was determined. The phytochemistry and antioxidant and anticholinesterase activities of S. poculata were investigated for the first time in this study. The crude extract of S. poculata exhibited a significant antioxidant effect as well as butyrylcholinesterase inhibitory activity. Ursolic acid (2) and cirsimaritin (4) possessed high butyrylcholinesterase inhibitory activity.
Antioxidant Properties of Rosa Pisiformis and Its Protective Effect Against Isoproterenol-Induced Oxidative Stress in Rats
(Walter de Gruyter Gmbh, 2016) Bayramoglu, Mahire; Ekin, Suat; Kiziltas, Hatice; Oto, Gokhan; Susen, Ebru Altindal; Ozgokce, Fevzi
Objective: In this study, Rosa pisiformis was evaluated for its antioxidant activity, vitamin (A, E, C), trace element (Fe, Cu, Zn, Mn, Cr, Se) and mineral (Ca, K, Mg, Na) levels, in addition to its cardioprotective effects on cardiac tissue antioxidant enzymes (GSH-Px, SOD, CAT) during isoproterenol (ISO)-induced oxidative stress. Methods: In the study, vitamin and mineral analysis was carried out using HPLC and ICP-MS method, R. P. antioxidant and antiradical properties were determined using spectrophotometer. Forty wistar albino rats were divided into four groups: control (0.9% NaCl), ISO (100 mg/kg), ISO (100 mg/kg) + R. P. (300 mg/kg) and R. P. (300 mg/kg). ISO was injected subcutaneously into rats twice at an interval of 24 h for two consecutive days (on 28(th) and 29(th) day). R. P. fruit administered daily. The experimental period was continued for 30 days. Results: The results of the study indicated that R. P. fruit and leaves contain high levels of minerals and vitamins and possess antioxidant and antiradical activity and its fruits have positive effects on cardiac tissues. The results are supported with significant changes in antioxidant enzyme levels and histopathological examination. Conclusion: This study demonstrates that R. P. fruits in particular can be used to treat and prevent cardiac diseases.
Antiproliferative Activity of Malus Sylvestris Miller Against Hepg2 Cell Line With Their Antioxidant Properties and Phenolic Composition
(Walter de Gruyter Gmbh, 2023) Vuran, Nese Eray; Kartal, Deniz Irtem; Celik, Ismail
Objectives: The purpose of this study was to investigate the in vitro antiproliferative activities of Malus sylvestris Miller (MS) ethanolic and water extracts against HepG2 cells together with their antioxidant and phytochemical profiles.Methods: The extracts' antioxidant capacity was assessed by DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) methods and the total phenolic and flavonoid contents were measured spec-trophotometrically. The antiproliferative activities of ex -tracts were tested via XTT colorimetric assay. The phenolic compounds in the extracts were analyzed using HPLC-DAD analysis.Results: The most abundant phenolic compounds in both extract types were rutin, chlorogenic and gallic acid. In parallel to the phenolic composition, the ethanolic extracts showed the higher antioxidant activity, total phenolic and flavonoid content than the water extracts. The ethanolic extracts displayed 4.5-fold more antiproliferative activity than the water extracts against HepG2 cells. The IC50 values for the ethanolic and water extracts of MS were 0.86 and 3.95 mg/mL, respectively.Conclusions: These results contributed to the understanding of the cytotoxic potential of MS. Since wild apple exhibited strong cytotoxic activity against HepG2 cells, it may be used as a natural agent to treat cancer and the further studies are needed to reveal the effects of wild apple on cancer.
Aşırı Değerlenmiş Düşüncelerin Ölçülmesi
(2005) Beşiroğlu, Lütfullah
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Association Between Pon1 L55m Polymorphism and Pon1 Enzyme Activity in Patients With Leukemia
(Akad Doktorlar Yayinevi, 2017) Eras, Nazan; Tombak, Anil; Tiftik, Naci; Yalin, Serap; Berkoz, Mehmet; Kul, Seval; Akbas, Etem
Paraoxonase 1 (PON1) is an important antioxidant enzyme which has a role in preventing the effects of systemic oxidative stress. The purpose of our study was to investigate the possible association between PON1 L55M polymorphism and leukemia development and to determine the relationship between PON1 genotypes and PON1 enzyme activities. Genotypes of 102 cases and 112 healthy controls were determined by PCR-RFLP. PON1 enzyme activity was determined according to Eckerson's method. The ratio of MM genotype belonging to PON1 L55M polymorphism in control group was 6.3% and was 7.8% in patients with leukemia (p= 0.39). PON1 enzyme activity was 118.8 +/- 115.1 U/mL in control group, while decreased to 75.6 +/- 64.4 U/mL in patients with leukemia (p= 0.004). PON1 enzyme activities of the individuals with MM genotypes belonging to PON1 L55M polymorphism was 57.43 21.61 U/ mL in control group and decreased to 39.18 +/- 45.61 U/mL in leukemic patients. Our results suggest that, PON1 L55M polymorphism genotype ratios do not affect leukemia development. However, reduced PON1 enzyme activity and also the combination of PON1 L55M polymorphism with reduced PON1 enzyme activity are associated with the increased risk of leukemia. Furthermore, older age may be a risk factor for developing leukemia.
Association of Pain and Clinical Factors on Disability and Quality of Life in Systemic Sclerosis: a Cross-Sectional Study From Turkish League Against Rheumatism Network
(Turkish League Against Rheumatism, 2023) Cevik, Remzi; Em, Serda; Nas, Kemal; Toprak, Murat; Cengiz, Gizem; Calis, Mustafa; Ecesoy, Hilal
Objectives: In this study, we aimed to evaluate the factors associated with disability and quality of life (QoL) in Turkish patients with systemic sclerosis (SSc). Patients and methods: Between January 2018 and January 2019, a total of 256 SSc patients (20 males, 236 females; mean age: 50.9 +/- 12.4 years; range, 19 to 87 years) who were diagnosed with SSc were included in the study. Disability and health-related QoL (HRQoL) were evaluated by the Health Assessment Questionnaire (HAQ), scleroderma HAQ (SHAQ), Duruoz Hand Index (DHI), and Short Form-36 (SF-36). Linear regression analysis methods were used to describe factors associated with disability and QoL of the patients. Results: All disability scores were higher and HRQoL scores were lower in diffuse cutaneous SSc patients compared limited cutaneous SSc, and differentiations were significant (p= 0.001 and p= 0.007). In multiple regression, pain (VAS) was the strongest predictor for high disability and low QoL scores (p<0.001) as HAQ (beta=0.397, 0.386, 0.452), SHAQ (beta=0.397, 0.448, 0.372), DHI (beta=0.446, 0.536, 0.389), PCS (beta=- 0.417,- 0.499, -0.408) and MCS (beta=-0.478, -0.441, -0.370) in combined, lcSSc and dcSSc patients respectively. The factors associated with high disability and low QoL scores were forced vital capacity for HAQ (beta=- 0.172, p=0.002) and SF-36 PCS (beta= 0.187, p= 0.001); disease duration for HAQ (beta=0.208, p<0.001), DHI (beta=0.147, p=0.006), and SF-36 PCS (beta=-0.134, p= 0.014); 6-minute walk test for HAQ (beta=- 0.161, p= 0.005) and SF-36 PCS (beta= 0.153, p=0.009); and modified Rodnan skin score for SHAQ (beta= 0.250, p<0.001) and DHI (beta=0.233, p<0.001) in SSc patients. Diffusing capacity of the lungs for carbon monoxide for HAQ (beta=- 0.189, p=0.010) and SHAQ (beta=-0.247, p= 0.002); erythrocyte sedimentation rate for DHI (beta=0.322, p<0.001); age for SF-36 PCS (beta=-0.221, p=0.003) and body mass index for SF-36 PCS (beta=-0.200, p=0.008) and MCS (beta=-0.175, p=0.034) were the other variables associated with high disability or low QoL scores in SSc subsets. Conclusion: Clinicians should consider the management of the pain and its sources as a key to improve better functional state and quality of daily life in SSc.
The Association of Short Segment Barrett's Esophagus With Intestinal Metaplasia in Stomach
(2003) Tuncer, I.; Ugraş, S.; Uygan, I.; Türkdoǧan, K.; Kösem, M.
Background/aims: The aims of this study were to investigate the presence of short segment Barrett's esophagus in people found to have tongue-like columnar mucosal protrusions in the distal esophagus and to determine the relationship between short segment Barrert's esophagus and Helicobacter pylori, gastritis and intestinal metaplasia observed in other parts of the stomach. Methods: The study included 50 patients (32 male, 18 female). Two biopsy specimens were taken from the antrum, at least 2 cm away from the pylorus, from the incisura angularis, corpus and cardia and four biopsy specimens were taken from tongue-like columnar protrusions (<3 cm long) above the gastroesophageal junction. Tissue samples were stained with hematoxyline-eosine, HID-Alcian blue pH 2.5 and modified Giemsa. Results: Of the 50 subjects who were found to have tongue-like columnar protrusions above the gastroesophageal junction, short segment Barrett's esophagus was detected in nine (18%). Whereas all short segment Barretti's esophagus cases were associated with chronic gastritis, Helicobacter pylori was found to be positive in five (55.5%) of them and there was intestinal metaplasia in other parts of the stomach (antrum in two patients, incisura angularis in three, antrum and cardia in one) in six (66.6%) cases. In 41 patients without short segment Barrett's esophagus 33 (80%) had chronic gastritis, 27 (66%) had Helicobacter pylori infection and eight had intestinal metaplasia in different locations (there in antrum, four in incisura angularis, one in the antrum and cardia) of the stomach. Conclusions: An association between short segment Barrett's esophagus and intestinal metaplasia was found in different parts of the stomach. The link between intestinal metaplasia in the stomach and these metaplastic changes in the tubular esophagus requires evalation in larger and more comprehensive studies.
Autosomal Recessive Hypophosphatemic Rickets Type 2; a Novel Mutation in the Enpp1 Gene
(Turkish J Pediatrics, 2022) Bitkin, Eda Celebi; Aymelek, Huri Sema
Background. Hypophosphatemic rickets (HR) is a rare disease caused by several genetic mutations in factors that cause an increase in fibroblast growth factor 23 (FGF23), and renal phosphate transporters. ENPP1 (ectonucleotide pyrophosphatase / phosphodiesterase 1) mutations cause autosomal recessive inheritance hypophosphatemic rickets type 2. Case. In our study, we present a novel mutation in the ENPP1 gene detected in 4 siblings in a single family. Conclusion. Our findings can be applied to further understand molecular pathogenesis and to establish a correlation between genotype and phenotype for HR.
Avipoxvirus Infection in Quails
(Tubitak Scientific & Technological Research Council Turkey, 2005) Gülbahar, MY; Çabalar, M; Boynukara, B
The present study describes clinical, virological, histopathological, immunohistochemical and electron microscopic findings of pox infection encountered in a quail flock. Lesions consisted of single or multiple nodules with a crust in variable size of gray to yellow or dark brown discoloration on the comb, eyelids, and the other poorly feathered areas of the body. Histopathological changes consisted of hyperplastic epithelium overlying, with ballooning degeneration of keratinocytes, many of which had eosinophilic intracytoplasmic inclusion bodies (Bollinger bodies), and heterophilic infiltrations admixed with mononuclear cells extending into dermis. Avipoxvirus infection was confirmed by positive immunostaining in the cytoplasm of affected cells for poxvirus antigen, excluded no immunostaining of inclusion bodies, using streptavidin-biotin peroxidase complex method and by demonstration of brick-shaped virus particles with a central core using direct electron microscopy. Typical thickness of chorio-allantoic membranes (CAMs) infected with virus, compared with controls, was observed, and the harvested virus on CAMs was detected as positive against known fowlpox virus using gel diffusion test.
Aykırı Değerlerin Tespiti ve Taşkın Debilerinin Hesabı için Bir Yöntem Geliştirilmesi
(2018) Tuna, Ahmet; Aydın, Mahsum
Bu çalışmada aykırı değerlerin belirlenmesi ve taşkın debilerinin hesabı için geliştirilen yeni bir metot önerilmektedir. Çalışmada Fırat havzası üzerinde bulunan 6 adet gözlem istasyonuna ait veriler kullanılmıştır. Bu gözlem istasyonlarına ait veriler analiz edilmiş ve aykırı değerler Rosner testi, Dixon Thompson testi ve önerilen yöntem ile tespit edilmiştir. Belirli tekerrür aralığında meydana gelebilecek olan taşkın debileri önerilen yöntem kullanılarak hesap edilmiştir. Aykırı değerler veri setlerinden çıkarılarak uyumun iyiliği testleri sonucu belirlenen olasılık yoğunluk fonksiyonları (OYF) kullanılarak taşkın debileri hesap edilmiştir. Ayrıca L momentler yöntemi ile parametreleri belirlenen en uygun OYF yardımıyla taşkın debileri bölgesel olarak hesap edilmiştir. Önerilen yöntem, taşkın frekans analizi ve L momentler yöntemi ile hesaplanan taşkın debisi değerleri karşılaştırıldığında önerilen yöntem ve noktasal taşkın frekans analizi ile belirlenen değerlerin L momentler yöntemi ile belirlenen değerlerden daha uygun ve kullanılabilir olduğu kanaatine varılmıştır
Baseline Clinical Characteristics and Patient Profile of the Turkmi Registry: Results of a Nation-Wide Acute Myocardial Infarction Registry in Turkey
(Kare Publ, 2020) Erol, Mustafa Kemal; Kayikcioglu, Meral; Kilickap, Mustafa; Arin, Can Baba; Kurt, Ibrahim Halil; Aktas, Ibrahim; Somuncu, Mustafa Umut
Objective: The TURKMI registry is designed to provide insight into the characteristics, management from symptom onset to hospital discharge, and outcome of patients with acute myocardial infarction (MI) in Turkey. We report the baseline and clinical characteristics of the TURKMI population. Methods: The TURKMI study is a nation-wide registry that was conducted in 50 centers capable of percutaneous coronary intervention selected from each EuroStat NUTS region in Turkey according to population sampling weight, prioritized by the number of hospitals in each region. All consecutive patients with acute MI admitted to coronary care units within 48 hours of symptom onset were prospectively enrolled during a predefined 2-week period between November 1, 2018 and November 16, 2018. Results: A total of 1930 consecutive patients (mean age, 62.0 +/- 13.2 years; 26.1% female) with a diagnosis of acute MI were prospectively enrolled. More than half of the patients were diagnosed with non-ST elevation MI (61.9%), and 38.1% were diagnosed with ST elevation MI. Coronary angiography was performed in 93.7% and, percutaneous coronary intervention was performed in 73.2% of the study population. Fibrinolytic therapy was administered to 13 patients (0.018%). Aspirin was prescribed in 99.3% of the patients, and 94% were on dual antiplatelet therapy at the time of discharge. Beta blockers were prescribed in 85.0%, anti-lipid drugs in 96.3%, angiotensin converting enzyme inhibitors in 58.4%, and angiotensin receptor blockers in 7.9%. Comparison with European countries revealed that TURKMI patients experienced MI at younger ages compared with patients in France, Switzerland, and the United Kingdom. The most prevalent risk factors in the TURKMI population were hypercholesterolemia (60.2%), hypertension (49.5%), smoking (48.8%), and diabetes (37.9%). Conclusion: The nation-wide TURKMI registry revealed that hypercholesterolemia, hypertension, and smoking were the most prevalent risk factors. TURKMI patients were younger compared with patients in European Countries. The TURKMI registry also confirmed that current treatment guidelines are largely adopted into clinical cardiology practice in Turkey in terms of antiplatelet, anti-ischemic, and anti-lipid therapy.
Bazı Sütlü Gıdalarda Stabhylococcus Aureus'un İzolasyonu,termonükleaz Aktivitesi ve Enterotoksijenik Özelliklerinin Araştırılması
(2003) Akkaya, Levent; Alişarlı, Mustafa; Sancak, Yakup Can; Elibol, Cihangir
Özet: Sütlü tatlılarda Staphylococcus aureus'un izolasyonu, termonükleaz aktivitesi ve enterotoksijenik özelliklerinin araştırıldığı bu çalışmada, Van'da bulunan 5 farklı pastahaneye ait 100 adedi puding türü (25 sütlaç, 30 keşkül, 25 supangile ve 20 kazandibi) ve 75 adedi kremalı pasta (25 sade kremalı, 25 kakaolu kremalı ve 25 meyveli kremalı) olan toplam 175 adet örnek analiz edilmiştir. Analiz bulgularına göre S. aureus; l sütlaç (%4), 3 keşkül (% 10), 4 supangile (% 16) ve 2 kazandibinde (%8) olmak üzere puding türü tatlıların % 10'unda ve 6 sade kremalı (% 24), 10 kakaolu kremalı (% 40) ve 4 meyveli kremalı (% 16) olmak üzere kremalı pasta örneklerinin ise % 27'sinde, toplam 30 (% 17) örnekte bulunmuştur. Bu örneklerin 27 (% 90)'sinde izole edilen S. aureus'larda termonükleaz aktivitesi pozitif sonuçlanmış ve 11 (% 37)'inin ise enterotoksin oluşturma yeteneğinde olduğu saptanmıştır. A tipi enterotoksin; keşkül, supangile, sade kremalı, meyveli kremalı pastada l ve kakaolu kremalı pastada 3 olmak üzere toplam 7 örnekte tespit edilmiştir. C tipi enterotoksin supangile ve kakaolu kremalı pastada bulunurken, A/B miks enterotoksini sütlaç ve sade kremalı pastada saptanmıştır. Enterotoksin oluşturan S. aureus'ların tamamı termonükleaz aktivitesi de göstermiştir. Sonuç olarak, stafilokokkal gıda intoksikasyonun oluşumu için, ısıtma işlemi ile mikroflorası elimine edilmiş ve sonra S. aureus ile kontamine olmuş gıdaların önemli rol oynadığı görüşü dikkate alınırsa, sütlü tatlıların enterotoksijenik stafilokoklar yönünden tüketici açısından potansiyel sağlık riski taşıdığı, ciddi bir kontrol sisteminin gerekliliği ve özellikle de personel ve işletme hijyenine önem verilmesinin zorunlu olduğu görüşüne varılmıştır.
Bazı Sütlü Tatlıların Mikrobiyolojik Kalitelerinin Belirlenmesi
(2002) Elibol, Cihangir; Alişarlı, Mustafa; Sancak, Yakup Can; Akkaya, Levent
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Bazı Tane Sorgum Çeşitlerinin Besin Madde Kompozisyonu ve Sindirilebilir Kuru Madde Veriminin Belirlenmesi
(2003) Nursoy, Hüseyin; Akdeniz, Hakkı; Yılmaz, İbrahim Hakkı; Karslı, Mehmet Akif
Bu çalışmada, Doğu Anadolu bölgesi koşullarına uygun ve yüksek besin madde verimine sahip tane sorgum çeşitlerinin belirlenmesi amaçlanmıştır. Bu amaçla, bitki materyali olarak Öğretmenoğlu, Akdarı, Aldan, Beydan, Ramada, A-298, DK-64 ve KS-397 olmak üzere sekiz adet tane sorgum çeşidi kullanılmıştır. Tanelerini olgunlaştıran sorgum çeşitlerinin önce başakları ve hemen sonra hasılları elle hasat edilmiştir. Örneklerin kuru madde (KM), organik madde (OM), ham protein (HP), nötral deterjant fiber (NDF) ve asit deterjant fiber (ADF), in vitro sindirilebilirlik düzeyleri ile KM verimi ve Sindirilebilir KM verimleri belirlenmiştir. Hasılların KM düzeyleri % 26,64-35,36 arasında bulunmuştur (P < 0,05). Ramada ve Aldan çeşitlerinin hasıllarına ait OM düzeyleri diğer çeşitlerin hasıllarına ait OM düzeylerinden daha düşük olarak bulunmuştur (P < 0,05). Hasıllara ait NDF ve ADF içeriği Beydarfda en yüksek, DK-64 çeşidinde ise en düşük olduğu görülmüştür (P < 0,05). Hasıllara ait en yüksek in vitro sindilebilirlik, KM verimi ve Sindirilebilir KM verimi DK-64 ve Aldan çeşitlerinde elde edilmiştir (P < 0,05). Çeşitler içerisinde Öğretmenoğlu'na ait taneler en yüksek HP, ancak Beydarı ile birlikte en düşük in vitro sindirilebilirliliğe sahip olduğu görülmüştür (P < 0,05). KM verimi ve Sindirilebilir KM verimi bakımından en yüksek verim Ramada çeşidine ait tanelerden elde edilmiştir (P < 0,05). Toplam (tane + hasıl) KM verimi, Sindirilebilir KM verimi ve HP verimi Ramada ve A-298 çeşitlerinde diğer çeşitlere oranla daha yüksek bulunmuştur (P < 0,05). Sonuç olarak, Sindirilebilir KM ve HP verimleri baz alındığında, yetiştirilen sorgum çeşitleri arasında bölge şartlarına uygun en yüksek verim Ramada çeşidinden alınmış ve bunu sırasıyla A-298 ve Aldan çeşitleri izlemiştir.

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