Acute Effects of Fenthion on Certain Oxidative Stress Biomarkers in Various Tissues of Frogs (Rana Ridibunda)
| dc.contributor.author | Kanter, Ahmet | |
| dc.contributor.author | Celik, Ismail | |
| dc.date.accessioned | 2025-05-10T16:48:26Z | |
| dc.date.available | 2025-05-10T16:48:26Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | This study was aimed mainly to assess the effects of fenthion on certain oxidative stress biomarkers in various tissues of frogs (Rana ridibunda). Biomarkers selected for stress monitoring were malondialdehyde (MDA) and antioxidant defense system (ADS) such as reduced glutathione (GSH) level, glutathione peroxidase (GSH-Px), glutathione-S-transferase (GST), and superoxide dismutase (SOD) activities in the liver, kidney, heart, and brain of frogs exposed to 10 and 20 ppm dosages of fenthion for 24, 48, 72, and 96 h. The results demonstrate an increase in MDA levels in selected tissues following exposure to both concentrations of fenthion. The ADS, GSH-Px, GST, SOD activities and GSH levels also fluctuated after 24, 48, 72, and 96 h in all the treatment groups compared with controls. From the evidence obtained here, it is concluded that the exposure of frogs to fenthion induced an increase in MDA combined with fluctuated ADS. This may reflect the potential role of these parameters as useful biomarkers for oxidative stress in amphibian species. | en_US |
| dc.description.sponsorship | University of Yuzuncu Yil Grant Commission [YYU-BAP-2009-FBE-YL003] | en_US |
| dc.description.sponsorship | The study received financial assistance from the University of Yuzuncu Yil Grant Commission during the tenure of research numbered with YYU-BAP-2009-FBE-YL003. | en_US |
| dc.identifier.doi | 10.1177/0748233711412426 | |
| dc.identifier.issn | 0748-2337 | |
| dc.identifier.issn | 1477-0393 | |
| dc.identifier.scopus | 2-s2.0-84861798953 | |
| dc.identifier.uri | https://doi.org/10.1177/0748233711412426 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/1535 | |
| dc.language.iso | en | en_US |
| dc.publisher | Sage Publications inc | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Rana Ridibunda | en_US |
| dc.subject | Fenthion | en_US |
| dc.subject | Antioxidant Defense Systems | en_US |
| dc.subject | Lipid Peroxidation | en_US |
| dc.title | Acute Effects of Fenthion on Certain Oxidative Stress Biomarkers in Various Tissues of Frogs (Rana Ridibunda) | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.scopusid | 55240064200 | |
| gdc.author.scopusid | 8452071500 | |
| gdc.author.wosid | Çelik, İsmail/M-5085-2018 | |
| gdc.coar.access | metadata only access | |
| gdc.coar.type | text::journal::journal article | |
| gdc.description.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| gdc.description.departmenttemp | [Kanter, Ahmet; Celik, Ismail] Yuzuncu Yil Univ, Dept Biol, TR-65080 Van, Turkey | en_US |
| gdc.description.endpage | 376 | en_US |
| gdc.description.issue | 4 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q3 | |
| gdc.description.startpage | 369 | en_US |
| gdc.description.volume | 28 | en_US |
| gdc.description.woscitationindex | Science Citation Index Expanded | |
| gdc.description.wosquality | Q4 | |
| gdc.identifier.pmid | 21859772 | |
| gdc.identifier.wos | WOS:000302628600010 | |
| gdc.index.type | WoS | |
| gdc.index.type | Scopus | |
| gdc.index.type | PubMed |