Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients With Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study

dc.authorscopusid 7006287366
dc.authorscopusid 23478299500
dc.authorscopusid 57195443435
dc.authorscopusid 57079880500
dc.authorscopusid 57219410447
dc.authorscopusid 57219124259
dc.authorscopusid 56084897800
dc.authorwosid Ergen, Şefika/Aag-5533-2019
dc.authorwosid Ocak, Birol/Aec-2238-2022
dc.authorwosid Ucar, Gokhan/Aaa-8198-2021
dc.authorwosid Beypınar, İsmail/Aan-1107-2020
dc.authorwosid Kaytan Saglam, Esra/Oth-8852-2025
dc.authorwosid Gülmez, Ahmet/Abi-8218-2020
dc.authorwosid Öksüz, Didem/D-2649-2019
dc.contributor.author Uysal, Mukremin
dc.contributor.author Saglam, Sezer
dc.contributor.author Beypinar, Ismail
dc.contributor.author Saglam, Esra Kaytan
dc.contributor.author Mammadov, Elkhan
dc.contributor.author Ocak, Birol
dc.contributor.author Karabulut, Bulent
dc.date.accessioned 2025-12-30T16:05:34Z
dc.date.available 2025-12-30T16:05:34Z
dc.date.issued 2025
dc.department T.C. Van Yüzüncü Yıl Üniversitesi en_US
dc.department-temp [Uysal, Mukremin] Antalya Bilim Univ, Medstar Antalya Hosp, Dept Med Oncol, Antalya, Turkiye; [Saglam, Sezer] Istanbul Bilim Univ, Dept Med Oncol, Istanbul, Turkiye; [Beypinar, Ismail] Afyonkarahisar Hlth Sci Univ, Dept Med Oncol, Afyonkarahisar, Turkiye; [Saglam, Esra Kaytan] Istanbul Univ, Dept Radiat Oncol, Istanbul, Turkiye; [Mammadov, Elkhan; Bilici, Ahmet] Medipol Univ, Dept Med Oncol, Istanbul, Turkiye; [Ocak, Birol] Uludag Univ, Dept Med Oncol, Bursa, Turkiye; [Aybi, Ozge; Kilickap, Saadettin] Hacettepe Univ, Canc Inst, Dept Med Oncol, Ankara, Turkiye; [Arikan, Rukiye; Alan, Ozkan] Marmara Univ, Sch Med, Dept Internal Med, Div Med Oncol, Istanbul, Turkiye; [Ergen, Sefika Arzu; Oksuz, Didem Colpan] Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Radiat Oncol, Istanbul, Turkiye; [Gursoy, Pinar; Karabulut, Bulent] Ege Univ, Sch Med, Dept Internal Med, Div Med Oncol, Izmir, Turkiye; [Sakin, Abdullah] Yuzuncu Yil Univ, Fac Med, Dept Med Oncol, Van, Turkiye; [Kaya, Vildan] Medstar Antalya Hosp, Dept Radiat Oncol, Antalya, Turkiye; [Ozden, Ercan] Kocaeli Univ, Sch Med, Dept Med Oncol, Kocaeli, Turkiye; [Eren, Tulay] Diskapi Yildirim Beyazit Training & Res Hosp, Dept Med Oncol, Ankara, Turkiye; [Demiray, Atike Gokcen] Pamukkale Univ, Sch Med, Med Oncol Dept, Denizli, Turkiye; [Oyman, Abdilkerim] Univ Hlth Sci, Istanbul Umraniye Training & Res Hosp, Dept Med Oncol, Istanbul, Turkiye; [Tatli, Ali Murat] Akdeniz Univ, Sch Med, Dept Med Oncol, Antalya, Turkiye; [Turk, Haci Mehmet] Bezmialem Vakif Univ, Dept Med Oncol, Istanbul, Turkiye; [Gulmez, Ahmet] Inonu Univ, Dept Med Oncol, Malatya, Turkiye; [Demir, Atakan] Acibadem Univ, Div Med Oncol, Sch Med, Acibadem, Turkiye; [Sakalar, Teoman] Aksaray Training & Res Hosp, Aksaray, Turkiye; [Sen, Erdem] Mehmet Akif Ersoy State Hosp, Canakkale, Turkiye; [Ucar, Gokhan] Ankara Numune Training & Res Hosp, Dept Med Oncol, Ankara, Turkiye en_US
dc.description.abstract The goal of this study was to look at the long-term survival outcomes and clinical characteristics of stage II/III locally advanced rectal cancer (LARC) patients who acquired pathological complete response (pCR) following neoadjuvant chemoradiotherapy (NCRT). The clinicopathological characteristics and treatment details of 277 LARC patients with pCR, relapse-free survival (RFS), overall survival (OS), and locoregional and systemic recurrence rates, were assessed. The 5-year RFS and OS rates were 85.6% and 90.9%. The rates of local and systemic recurrence were 3.6% and 7.9%. Our study confirmed the favorable results in survival in patients with LARC who achieved pCR en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.doi 10.1080/07357907.2025.2595536
dc.identifier.issn 0735-7907
dc.identifier.issn 1532-4192
dc.identifier.pmid 41347635
dc.identifier.scopus 2-s2.0-105024909531
dc.identifier.scopusquality Q3
dc.identifier.uri https://doi.org/10.1080/07357907.2025.2595536
dc.identifier.uri https://hdl.handle.net/20.500.14720/29335
dc.identifier.wos WOS:001631349200001
dc.identifier.wosquality Q3
dc.language.iso en en_US
dc.publisher Taylor & Francis Inc en_US
dc.relation.ispartof Cancer Investigation en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Disease-Free Survival en_US
dc.subject Local Recurrence en_US
dc.subject Local Advanced Rectal Cancer en_US
dc.subject Neoadjuvant Chemoradiation en_US
dc.subject Pathological Complete Response en_US
dc.subject Overall Survival en_US
dc.subject Surgical Outcome en_US
dc.title Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients With Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.coar.access metadata only access
gdc.coar.type text::journal::journal article

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