Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients With Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study
| dc.contributor.author | Uysal, Mukremin | |
| dc.contributor.author | Saglam, Sezer | |
| dc.contributor.author | Beypinar, Ismail | |
| dc.contributor.author | Saglam, Esra Kaytan | |
| dc.contributor.author | Mammadov, Elkhan | |
| dc.contributor.author | Ocak, Birol | |
| dc.contributor.author | Karabulut, Bulent | |
| dc.date.accessioned | 2025-12-30T16:05:34Z | |
| dc.date.available | 2025-12-30T16:05:34Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | The goal of this study was to look at the long-term survival outcomes and clinical characteristics of stage II/III locally advanced rectal cancer (LARC) patients who acquired pathological complete response (pCR) following neoadjuvant chemoradiotherapy (NCRT). The clinicopathological characteristics and treatment details of 277 LARC patients with pCR, relapse-free survival (RFS), overall survival (OS), and locoregional and systemic recurrence rates, were assessed. The 5-year RFS and OS rates were 85.6% and 90.9%. The rates of local and systemic recurrence were 3.6% and 7.9%. Our study confirmed the favorable results in survival in patients with LARC who achieved pCR | en_US |
| dc.identifier.doi | 10.1080/07357907.2025.2595536 | |
| dc.identifier.issn | 0735-7907 | |
| dc.identifier.issn | 1532-4192 | |
| dc.identifier.scopus | 2-s2.0-105024909531 | |
| dc.identifier.uri | https://doi.org/10.1080/07357907.2025.2595536 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/29335 | |
| dc.language.iso | en | en_US |
| dc.publisher | Taylor & Francis Inc | en_US |
| dc.relation.ispartof | Cancer Investigation | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Disease-Free Survival | en_US |
| dc.subject | Local Recurrence | en_US |
| dc.subject | Local Advanced Rectal Cancer | en_US |
| dc.subject | Neoadjuvant Chemoradiation | en_US |
| dc.subject | Pathological Complete Response | en_US |
| dc.subject | Overall Survival | en_US |
| dc.subject | Surgical Outcome | en_US |
| dc.title | Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients With Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.scopusid | 7006287366 | |
| gdc.author.scopusid | 23478299500 | |
| gdc.author.scopusid | 57195443435 | |
| gdc.author.scopusid | 57079880500 | |
| gdc.author.scopusid | 57219410447 | |
| gdc.author.scopusid | 57219124259 | |
| gdc.author.scopusid | 56084897800 | |
| gdc.author.wosid | Ergen, Şefika/Aag-5533-2019 | |
| gdc.author.wosid | Ocak, Birol/Aec-2238-2022 | |
| gdc.author.wosid | Ucar, Gokhan/Aaa-8198-2021 | |
| gdc.author.wosid | Beypınar, İsmail/Aan-1107-2020 | |
| gdc.author.wosid | Kaytan Saglam, Esra/Oth-8852-2025 | |
| gdc.author.wosid | Gülmez, Ahmet/Abi-8218-2020 | |
| gdc.author.wosid | Öksüz, Didem/D-2649-2019 | |
| gdc.coar.access | metadata only access | |
| gdc.coar.type | text::journal::journal article | |
| gdc.description.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| gdc.description.departmenttemp | [Uysal, Mukremin] Antalya Bilim Univ, Medstar Antalya Hosp, Dept Med Oncol, Antalya, Turkiye; [Saglam, Sezer] Istanbul Bilim Univ, Dept Med Oncol, Istanbul, Turkiye; [Beypinar, Ismail] Afyonkarahisar Hlth Sci Univ, Dept Med Oncol, Afyonkarahisar, Turkiye; [Saglam, Esra Kaytan] Istanbul Univ, Dept Radiat Oncol, Istanbul, Turkiye; [Mammadov, Elkhan; Bilici, Ahmet] Medipol Univ, Dept Med Oncol, Istanbul, Turkiye; [Ocak, Birol] Uludag Univ, Dept Med Oncol, Bursa, Turkiye; [Aybi, Ozge; Kilickap, Saadettin] Hacettepe Univ, Canc Inst, Dept Med Oncol, Ankara, Turkiye; [Arikan, Rukiye; Alan, Ozkan] Marmara Univ, Sch Med, Dept Internal Med, Div Med Oncol, Istanbul, Turkiye; [Ergen, Sefika Arzu; Oksuz, Didem Colpan] Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Radiat Oncol, Istanbul, Turkiye; [Gursoy, Pinar; Karabulut, Bulent] Ege Univ, Sch Med, Dept Internal Med, Div Med Oncol, Izmir, Turkiye; [Sakin, Abdullah] Yuzuncu Yil Univ, Fac Med, Dept Med Oncol, Van, Turkiye; [Kaya, Vildan] Medstar Antalya Hosp, Dept Radiat Oncol, Antalya, Turkiye; [Ozden, Ercan] Kocaeli Univ, Sch Med, Dept Med Oncol, Kocaeli, Turkiye; [Eren, Tulay] Diskapi Yildirim Beyazit Training & Res Hosp, Dept Med Oncol, Ankara, Turkiye; [Demiray, Atike Gokcen] Pamukkale Univ, Sch Med, Med Oncol Dept, Denizli, Turkiye; [Oyman, Abdilkerim] Univ Hlth Sci, Istanbul Umraniye Training & Res Hosp, Dept Med Oncol, Istanbul, Turkiye; [Tatli, Ali Murat] Akdeniz Univ, Sch Med, Dept Med Oncol, Antalya, Turkiye; [Turk, Haci Mehmet] Bezmialem Vakif Univ, Dept Med Oncol, Istanbul, Turkiye; [Gulmez, Ahmet] Inonu Univ, Dept Med Oncol, Malatya, Turkiye; [Demir, Atakan] Acibadem Univ, Div Med Oncol, Sch Med, Acibadem, Turkiye; [Sakalar, Teoman] Aksaray Training & Res Hosp, Aksaray, Turkiye; [Sen, Erdem] Mehmet Akif Ersoy State Hosp, Canakkale, Turkiye; [Ucar, Gokhan] Ankara Numune Training & Res Hosp, Dept Med Oncol, Ankara, Turkiye | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q3 | |
| gdc.description.woscitationindex | Science Citation Index Expanded | |
| gdc.description.wosquality | Q3 | |
| gdc.identifier.pmid | 41347635 | |
| gdc.identifier.wos | WOS:001631349200001 | |
| gdc.index.type | WoS | |
| gdc.index.type | Scopus | |
| gdc.index.type | PubMed |