Primary Central Nervous System Lymphoma in Daily Practice and the Role of Autologous Stem Cell Transplantation in Relapsed Disease: a Retrospective Multicenter Study
| dc.authorid | Kuku, Irfan/0000-0001-6126-0816 | |
| dc.authorid | Dogu, Mehmet Hilmi/0000-0001-7237-2637 | |
| dc.authorid | Demir, Cengiz/0000-0001-9856-184X | |
| dc.authorid | Altuntas, Fevzi/0000-0001-6872-3780 | |
| dc.authorid | Berber, Ilhami/0000-0003-3312-8476 | |
| dc.authorid | Erkurt, Mehmet Ali/0000-0002-3285-417X | |
| dc.authorid | Kaya, Emin/0000-0001-8605-8497 | |
| dc.authorscopusid | 8842895600 | |
| dc.authorscopusid | 55274431700 | |
| dc.authorscopusid | 15756259700 | |
| dc.authorscopusid | 55212747300 | |
| dc.authorscopusid | 14022986200 | |
| dc.authorscopusid | 8518945300 | |
| dc.authorscopusid | 56370690600 | |
| dc.authorwosid | Şencan, Mehmet/Aaa-9163-2022 | |
| dc.authorwosid | Yilmaz, Mehmet/Jwo-1749-2024 | |
| dc.authorwosid | Doğan, Mehmet/A-6890-2015 | |
| dc.authorwosid | Demir, Cengiz/Jze-3811-2024 | |
| dc.authorwosid | Bilen, Yusuf/Abh-9885-2022 | |
| dc.authorwosid | Sarı, Ismail/Lce-8798-2024 | |
| dc.authorwosid | Kaya, Emin/W-2951-2017 | |
| dc.contributor.author | Erkurt, Mehmet Ali | |
| dc.contributor.author | Berber, Ilhami | |
| dc.contributor.author | Tekgunduz, Emre | |
| dc.contributor.author | Dogu, Mehmet Hilmi | |
| dc.contributor.author | Korkmaz, Serdal | |
| dc.contributor.author | Demir, Cengiz | |
| dc.contributor.author | Aydogdu, Ismet | |
| dc.date.accessioned | 2025-05-10T17:39:35Z | |
| dc.date.available | 2025-05-10T17:39:35Z | |
| dc.date.issued | 2016 | |
| dc.department | T.C. Van Yüzüncü Yıl Üniversitesi | en_US |
| dc.department-temp | [Erkurt, Mehmet Ali; Berber, Ilhami; Kaya, Emin; Kuku, Irfan] Inonu Univ, Fac Med, Dept Hematol, TR-44069 Malatya, Turkey; [Tekgunduz, Emre; Altuntas, Fevzi; Dal, Mehmet Sinan] Ankara Oncol Hosp, Hematol & HCT Clin, Ankara, Turkey; [Dogu, Mehmet Hilmi; Sari, Ismail] Pamukkale Univ, Fac Med, Dept Hematol, Denizli, Turkey; [Korkmaz, Serdal] Kayseri Trainer & Res Hosp, Div Hematol, Kayseri, Turkey; [Demir, Cengiz] Yuzuncu Yil Univ, Fac Med, Dept Hematol, Van, Turkey; [Yilmaz, Mehmet] Antep Univ, Fac Med, Dept Hematol, Gaziantep, Turkey; [Akay, Olga Meltem] Osmangazi Univ, Fac Med, Dept Hematol, Eskisehir, Turkey; [Pala, Cigdem] Erciyes Univ, Fac Med, Dept Hematol, Kayseri, Turkey; [Bilen, Yusuf] Ataturk Univ, Fac Med, Dept Hematol, Erzurum, Turkey; [Sencan, Mehmet] Cumhuriyet Univ, Fac Med, Dept Hematol, Sivas, Turkey; [Altuntas, Fevzi] Yildirim Beyazit Univ, Fac Med, Dept Internal Med, Div Hematol, Ankara, Turkey; [Aydogdu, Ismet] Celal Bayar Univ, Fac Med, Dept Hematol, Manisa, Turkey | en_US |
| dc.description | Kuku, Irfan/0000-0001-6126-0816; Dogu, Mehmet Hilmi/0000-0001-7237-2637; Demir, Cengiz/0000-0001-9856-184X; Altuntas, Fevzi/0000-0001-6872-3780; Berber, Ilhami/0000-0003-3312-8476; Erkurt, Mehmet Ali/0000-0002-3285-417X; Kaya, Emin/0000-0001-8605-8497 | en_US |
| dc.description.abstract | We investigated the course of 54 patients presenting with primary central nervous system lymphoma, who were treated in daily practice. The patients were treated with chemotherapy and/or radiotherapy and/or intrathecal chemotherapy. At a median follow-up period of 23 months (range 1-71), median relapse-free survival (RFS) and overall survival (OS) were not reached. Estimated 2-year RFS and OS rates were 42% and 48%, respectively. Ten relapsed PCNSL patients underwent ASCT. Complete remission rate of these patients was 40%, with 20% treatment-related mortality. Estimated 2-year RFS and OS rates were 37% and 40%, respectively. The prognosis of patients with PCNSL, who received off-study treatment, is still dismal. (c) 2016 Elsevier Ltd. All rights reserved. | en_US |
| dc.description.woscitationindex | Science Citation Index Expanded | |
| dc.identifier.doi | 10.1016/j.transci.2016.01.018 | |
| dc.identifier.endpage | 84 | en_US |
| dc.identifier.issn | 1473-0502 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.pmid | 26810141 | |
| dc.identifier.scopus | 2-s2.0-84956890309 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 80 | en_US |
| dc.identifier.uri | https://doi.org/10.1016/j.transci.2016.01.018 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14720/14930 | |
| dc.identifier.volume | 54 | en_US |
| dc.identifier.wos | WOS:000374614700015 | |
| dc.identifier.wosquality | Q4 | |
| dc.language.iso | en | en_US |
| dc.publisher | Pergamon-elsevier Science Ltd | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Autologous Stem Cell Transplantation | en_US |
| dc.subject | Cns Lymphoma | en_US |
| dc.subject | Pcnsl | en_US |
| dc.subject | Methotrexate | en_US |
| dc.subject | High-Dose Chemotherapy | en_US |
| dc.title | Primary Central Nervous System Lymphoma in Daily Practice and the Role of Autologous Stem Cell Transplantation in Relapsed Disease: a Retrospective Multicenter Study | en_US |
| dc.type | Article | en_US |